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mechanism of disease > Introduction > Flashcards

Introduction Flashcards

1
Q

Pathology

A

Study of diseases

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2
Q

Period of supernatural

A

Beliefs in the early times that diseases were due to supernatural forces

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3
Q

Period of humors

A

Diseases were attributed to accumulation of body humors

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4
Q

Period of abiogenesis

A

Diseases were believed to be spontaneous processes

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5
Q

Period of modern pathology

A

Causation of diseases clear due to new techniques ( autopsy, cell patho etc)

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6
Q

Who debunked the theory of abiogenesis

A

Louis Pasteur

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7
Q

Who showed that change at cellular level is basis of disease

A

Rudolf virchow

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8
Q

Clinical pathology

A

Study of disease based on observation of the patients

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9
Q

Experimental pathology

A

Observation of effects on experimental systems

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10
Q

Gross pathology

A

Naked eye appearance

Macroscopic appearance

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11
Q

Autopsy

A

Direct inspection and analysis of organs to determine the specific cause of death

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12
Q

Tissue processing steps

A 
Fixation 
Impregnating 
Slicing 
Staining 
 Mounting
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13
Q

Fixation of tissue role

A

Preserve the tissue in the state it was obtained

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14
Q

Solution used for Fixation

A

10% buffered Formalin

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15
Q

Substance used for impregnating tissue

A

Paraffin wax

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16
Q

What is a frozen section

A

Freezing a tissue to analyze it rapidly

17
Q

Name of Routine staining

A

H&E

18
Q

Disease definition

A

Presence of an abnormality leads to loss of normal health

19
Q

List of Etiological agents of diseases

A

Genetically abnormality
Infectious agents
Chemicals
Physical agents

20
Q

Primary / idiopathic disease

A

Cause of disease is unknown

21
Q

Secondary disease

A

The cause of the disease is known

22
Q

Risk factors of diseases

A

They are agents that make people more at risks of developing a specific disease ( like smoking etc )

23
Q

Predisposition

A

Increased risk of having a disease

Can be genetic, environmental or infectious

24
Q

Morbidity

A

The sum of effects of the disease of a person

25
Q

Mortality

A

The probability that death will be the outcome

26
Q

Crude death rate

A

Number of deaths per year per 1000 people

8.23 per 1000 per year rn

27
Q

Case fatality rate

A

Percentage of persons presenting with disease who died

28
Q

Acute disease

A

Rapid onset of disease with rapid resolution

29
Q

Chronic disease

A

Prolonged duration of disease ( >3months)

30
Q

Benign

A

Prognosis of disease is good

31
Q

Malignant

A

Prognosis of disease is bad

mechanism of disease (22 decks)

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