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Clinical Pathology > Intro to Hematology > Flashcards

Intro to Hematology Flashcards

1
Q

pathology

A

study of the causes, mechanisms, and effects of diseases, including the examination of body tissues, fluids, and organs

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2
Q

clinical pathology

A

subspecialty of pathology that focuses on the diagnosis and monitoring of diseases based on lab testing on various bodily fluids

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3
Q

sections of clinical pathology

A

hematology
chemistry
serology/immunology
tranfusion medicine
clinical microscopy
parasitology

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4
Q

hematology

A

study of blood cells and their formation
CBC
blood smear evaluation

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5
Q

CBC

A

RBC/WBC/platelet count
hemoglobin concentrations
PCV (packed cell volume)
differential WBC examination
calculation of absolute values
erythrocyte indices

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6
Q

blood smear evaluation

A

can be part of CBC

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7
Q

whole blood

A

RBC, WBC, platelets, plasma
55% plasma
45% RBC
<1% WBC/platelets

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8
Q

plasma components

A

90% water and proteins
10% hormones/enzymes, nutrients, gases

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9
Q

serum

A

liquid part of blood AFTER coagulation

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10
Q

plasma

A

liquid cell-free portion of blood
obtained after treated with anticoagulant

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11
Q

two classes of tubes

A

procoagulants
anticoagulants

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12
Q

procoagulants

A

yield serum
red or tiger top

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13
Q

red top

A

glass or plastic
glass - no additives
plastic - silicon coated

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14
Q

tiger top

A

wax separator

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15
Q

anticoagulant additives need to bind to

A

calcium

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16
Q

heparin

A

antithrombin
reversible
RBC measurements

17
Q

EDTA

A

preferred
binds to calcium
irreversible
hematology

18
Q

citrates

A

preferred for coag panel
binds to calcium
reversible

19
Q

order of blood tubes

A

blue
red
tiger top
green
purple
gray

20
Q

sample volume depends on

A

amount of serum/plasma needed
hydration of animal

21
Q

enough blood to run tests how many times

A

3

22
Q

consider what in regards to sample size

A

patient size

23
Q

most common automated analyzers

A

impedance analyzers
laser-based flow cytometer

24
Q

5 types of WBCs

A

neutrophils
eosinophils
basophils
lymphocytes
monocytes

25
Q

impedance analyzers

A

based on electric currents/disruptions to currents
uses adult size of cells

26
Q

laser-focused flow cytometry

A

focused laser beams evaluate size and density of solid components
degree and angles allow for enumeration of cells
dyes allow enumeration of mature vs immature RBCs

27
Q

histograms/scatter plots

A

provide visual rep of cells within a sample

28
Q

normal histogram - lymphocytes

A

50 - 100 fL

29
Q

normal histogram - mixed cell population

A

100 - 150 fL

30
Q

normal histogram - neutrophils

A

150 - 300 fL

31
Q

blood smear evaluation

A

different % of WBCs

Clinical Pathology (17 decks)

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