Hypersensitivity Flashcards

1
Q

Which hypersensitivities are mediated by immunoglobulins

A

I, II, and III

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2
Q

Which hypersensitivity is cell mediated

A

IV

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3
Q

What is Type I mediated by

A

IgE

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4
Q

What is Type II mediated by

A

IgG and IgM

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5
Q

What is Type III mediated by

A

IgG and IgM (mostly IgG)

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6
Q

What is Type IV mediated by

A

mast cells

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7
Q

Which hypersensitivity reaction is involved in seasonal allergies/anaphylaxis

A

Type I

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8
Q

Which hypersensitivity reaction is involved in direct cytotoxicity

A

Type II

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9
Q

Which hypersensitivity reaction results in cellular and tissue damage due to association with antigen/antibody complexes

A

Type III

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10
Q

Which hypersensitivity reaction is associated with contact dermatitis or granuloma formation

A

Type IV

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11
Q

Do all hypersensitivities require a sensitization phase

A

Yes

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12
Q

Do all hypersensitivities require a second exposure

A

No

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13
Q

Which hypersensitivity reaction responds to soluble antigen

A

Type III

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14
Q

Which hypersensitivity reaction responds to bound antigens

A

Type II

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15
Q

What is a hypersensitivity reaction

A

an exaggerated or inappropriate response to a foreign or self antigen

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16
Q

Type I examples

A

seasonal allergies
food allergies

17
Q

Type II example

A

myasthenia gravis

18
Q

Type III example

A

rheumatoid arthritis

19
Q

Type IV example

A

contact dermatitis
multiple sclerosis