Hypersensitivity Flashcards
Which hypersensitivities are mediated by immunoglobulins
I, II, and III
Which hypersensitivity is cell mediated
IV
What is Type I mediated by
IgE
What is Type II mediated by
IgG and IgM
What is Type III mediated by
IgG and IgM (mostly IgG)
What is Type IV mediated by
mast cells
Which hypersensitivity reaction is involved in seasonal allergies/anaphylaxis
Type I
Which hypersensitivity reaction is involved in direct cytotoxicity
Type II
Which hypersensitivity reaction results in cellular and tissue damage due to association with antigen/antibody complexes
Type III
Which hypersensitivity reaction is associated with contact dermatitis or granuloma formation
Type IV
Do all hypersensitivities require a sensitization phase
Yes
Do all hypersensitivities require a second exposure
No
Which hypersensitivity reaction responds to soluble antigen
Type III
Which hypersensitivity reaction responds to bound antigens
Type II
What is a hypersensitivity reaction
an exaggerated or inappropriate response to a foreign or self antigen