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Yr1-S1- Science for Medicine > Intro to blood > Flashcards

Intro to blood Flashcards

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Biology 101 flashcards
1
Q

70kg man has …….. litres of blood

A

5

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2
Q

litres in systemic venous circulation

A

3

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3
Q

litres in lung

A

1

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4
Q

litres in heart and arterial circulation

A

1

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5
Q

Blood consists of

A

plasma
RBC
WBC
platelets

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6
Q

plasma

A

circulates biologically active molecules and compounds

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7
Q

3 categories of plasma proteins

A

albumin
globulin
fibrinogen

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8
Q

Plasma proteins generate an oncotic pressure of

A

about 25mmHg

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9
Q

plasma proteins do not readily cross the

A

capillary wall

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10
Q

movement of fluid between capillary and interstitial space is subject to two forces

A

capillary hydrostatic pressure

plasma protein concentration

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11
Q

capillary hydrostatic pressure

A

favours movement of fluid out of the capillary

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12
Q

plasma protein concentration

A

favours movement of fluid into capillary

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13
Q

causes of hypoproteinaemia

A

prolonger starvation
liver disease
intestinal diseases
nephrosis

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14
Q

erythrocyte

A

RBC

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15
Q

WBCs

A 
neutrophils
monocytes
basophils
eosinophil
lymphocyte
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16
Q

RBC lifespan

A

120 days

17
Q

erythropoiesis

A

RBC formation

pluripotent stem cells –> erythroblast (immature RBC)

18
Q

erythropoietin secretion is enhanced when

A

oxygen delivery to the kidneys is reduced (hypoxia)

19
Q

Leukocytes

A

white blood cells

1 x 10 (10) per litre

involved in defence against pathogens

20
Q

WBC - 2 types

A

granulocytes

agranulocytes

21
Q

Granulocytes

A

Neutrophils
Eosinophils
Basophils

22
Q

Agranulocytes

A

Monocytes

Lymphocytes (B cells and T cells) - 25%

(You get Helper T cells and Killer T cells)

23
Q

Neutrophils %

A

68

most abundant

24
Q

Monocytes

A

5% circulating cells

after 72 hours they migrate to connective tissue where they become marcophages and live for 3 months

25
Q

Leukopoiesis

A

WBC formation

26
Q

Cytokines are released from…

A

endothelial cells
fibroblasts
WBC

27
Q

Bacterial infection will increase

A

neutrophils

28
Q

Viral infection will increase

A

lymphocytes

29
Q

Platelets

A

membrane-bound cell fragments

formation governed by thrombopoietin

30
Q

Platelet life span

A

10 days

31
Q

plasma is …….X thicker than water

A

1.8

32
Q

whole blood is …… times thicker than water

A

3-4

Yr1-S1- Science for Medicine (19 decks)

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