immunology Flashcards

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1
Q

innate involves

A

phagocytes

neutrophils

macrophages

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2
Q

adaptive involves

A

lymphocytes

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3
Q

macrophage engulfs bacterium into a

A

phagosome

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4
Q

the phagosome then fuses with another vesicle called the

A

lysosome

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5
Q

lysosomes are full of chemicals and enzymes that will

A

kill the bacterium

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6
Q

monocytes and macrophages are made in

A

bone marrow (stem cells)

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7
Q

macrophages are found in

A

tissues

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8
Q

macrophages give off chemicals that

A

restrict blood flow away from the site of injury

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9
Q

macrophages produce

A

cytokines

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10
Q

neutrophils are also involved in

A

phagocytosis

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11
Q

eosinophil

A

parasitic infections

allergy and asthma

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12
Q

anaphylactic shock is caused by

A

mast cell degranulation

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13
Q

mast cells protect against

A

parasites

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14
Q

mast cells contain

A

histamine

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15
Q

basophil

A

store histamine

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16
Q

functions of complement

A

induce lysis of microbes MAC

promote phagocytosis

stimulate inflammation

17
Q

cytokinase

A

chemicals used by cells to communicate with other cells

18
Q

maturation of T cells and t cell precursors (macrophages, dendritic cells)

A

thymus

19
Q

spleen: white pulp has 2 zones

A

b cell and t cell

20
Q

spleen: red pulp

A

function is to filter blood

21
Q

t cell are responsible for

A

cell mediated immunity and assisting B cells

CD4 helper and CD8 killer

22
Q

t helper cells

A

cannot kill infected cells or pathogens

23
Q

cytotoxic t cells

A

when exposed to infeted cells they release perforin

form PORES in target cells

induce apoptosis

24
Q

Th2 cells

A

produce different potent cytokines which are regulating mast cells and eosinophil activity

25
Q

only ……… immune responses generate immunological memory

A

active

26
Q

plasma cells are responsible for ………. production

A

antibody

27
Q

B cells recognise self AG and

A

die in the bone marrow by apoptosis

28
Q

antibody structure light chain and heavy chain

A

binding region and Fc region