Forces acting against membranes Flashcards

1
Q

The cell membrane separates the

A

ECF and ICF

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2
Q

Cell membrane is responsible for maintaining

A

the difference in composition between the ECF and ICF

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3
Q

There is no barrier to

A

water movement

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4
Q

Ions can pass through the

A

capillary wall

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5
Q

K+ is high in…… and low in ….

A

ICF

ECF

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6
Q

Na+ is low in …. but high in ….

A

ICF

ECF

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7
Q

Cell membrane is a ………. barrier

A

selective

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8
Q

Permeability can…

A

vary

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9
Q

head of a phosphoplipid is

A

hydrophilic and lipophobic

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10
Q

tail of a phospholipid is

A

hydrophobic and lipophilic

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11
Q

There is also a difference in charge across the cell membrane. this creates….

A

an electrical gradient

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12
Q

To diffuse through the lipid bilayer molecules need to be

A

small
lipophilic
UNCHARGED

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13
Q

water can pass through

A

aquaporins

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14
Q

Voltage-gated channels

A

open/close in response to alterations in the membrane electrical potential (charge difference either side of the membrane)

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15
Q

Ligand gated channels

A

open/close when they blind a chemical such as neurotransmitter or hormone to a receptor binding site on the channel protein

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16
Q

Movement of molecules against their electrochemical gradients requires energy (ATP) and is known as

A

active transport

17
Q

H2O is inversely related to the

A

concentration of solute

18
Q

the more solute particles there are in solution - the more they will ………. H20

A

displace

therefore lowering the concentration of h20

19
Q

DIFFUSION

If a solution of different concentration is separated by a membrane permeable to water AND solute - then after time both will end up with equal ……. and equal ……..

A

concentration and volume

20
Q

If a solution of different concentration is separated by a membrane permeable ONLY to water - then after a time it will end up with…

A

equal concentrations either side of the membrane but

DIFFERENT VOLUMES

21
Q

Osmotic pressure

A

the pressure required to prevent water movement

22
Q

Osmolarity

A

measures the concentration of biological solutions in unit of OSMOLES and describes the number of particles/L in solution

23
Q

Normal human plasma osmolarity

the same as within cells

A

285 mOsmol/l (often 300)

24
Q

The cell volume at any time is dependent on the concentration of….

A

non-penetrating solutes on either side of the membrane

25
Q

Non-penetrating solutes

A

ECF = Na+ Cl-

ICF = K+

26
Q

Osmolarity

A

total number of particles in solution

27
Q

Tonicity

A

number of non-penetrating particles in solution

28
Q

tonicity is much more important as it determines

A

cell volume

29
Q

An iso-osmotic solution has

A

the same total number of solute particles as ECF (plasma)

30
Q

Hypo-osmotic

A

solutions with fewer total solute particles

31
Q

Hyper-osmotic

A

solution with greater number of total solute particles

32
Q

hypotonic

A

solutions with FEWER non-penetrating solute particles

33
Q

hypertonic

A

solution with greater number of non-penetrating solute particles

34
Q

cells in a hypotonic solution will

A

swell

water enters

35
Q

cells in a hypertonic solution will

A

shrink

water leaves