interleukins Flashcards

1
Q

What cytokine is involved in the pathophysiology of vasodilation → hypotension?

A

interleukin 1 , and increases vascular permeability.

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2
Q

what stimulates the proliferation of B cells?

A

IL-4
B cells produce both immunoglobulin M (IgM) and IgD

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3
Q

IL-4 promotes

A

class switching to IgE - important in defence against some parasitic diseases and in mast cell and basophil degranulation and antigen presentation

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4
Q

IL-5 stimulates the production of ?

A

eosinophils in response to parasitic infection and enhances class switching to IgA.

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5
Q

IL-8, along with other mediators such as C5a, leukotrienes B4, and bacterial products act as a?

A

chemotactic factors to lead neutrophils

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6
Q

one of the mediators of shock in sepsis is?

A

IL-1

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