HLA associations Flashcards
1
Q
HLA association for haemochromatosis ?
A
HLA-A3
2
Q
HLA association of Bechet disease (orogenital ulceration , eye inflammation uveitis , skin rashes and lesions,)
A
HLA-B51 on chromosome 6
3
Q
HLA association of ankylosing spondylitis ?
A
HLA-B27
4
Q
HLA association of reactive arthritis ?
A
HLA-B27
5
Q
HLA association of acute anterior uveitis
A
HLA- b27
6
Q
HLA ASSOCIATION OF CELIAC DISEASE
A
HLA-Dq2/8
7
Q
HLA -DR2 disease association?
A
narcolepsy
Goodpasture’s
8
Q
HLA-DR3 disease association
A
dermatitis herpetiformis
Sjögren’s syndrome
primary biliary cirrhosis
9
Q
HLA-DR4 disease association
A
type 1 diabetes mellitus
rheumatoid arthritis - in particular the DRB1 gene (DRB104:01 and DRB104:04 hence the association with DR4)
