Hodgkin's lymphoma Flashcards
1
Q
Hodgkin’s lymphoma
A
malignant proliferation of lymphocytes characterised by the presence of the Reed-Sternberg cell
2
Q
x
A
3
Q
x
A
4
Q
what else implies poor prognosis ?
A
‘B’ symptoms also imply a poor prognosis
weight loss > 10% in last 6 months
fever > 38ºC
night sweats
others :
age > 45 years
stage IV disease
haemoglobin < 10.5 g/dl
lymphocyte count < 600/µl or < 8%
5
Q
Histological classification Associated with worst prognosis ?
A
Lymphocyte depleted - Rare
6
Q
x
A
7
Q
x
A
8
Q
x
A
9
Q
x
A
10
Q
Histological classification most common form
A
Nodular sclerosing - good prognosis
11
Q
Histological classification Associated with a large number of Reed-Sternberg cells
A
Mixed cellularity - good prognosis
12
Q
Histological classification Associated with best prognosis ?
A
Lymphocyte predominant
13
Q
A
