Integumentary system Flashcards

1
Q

Pneumonic to remember the layers of skin

A

Come Lets Get Sun Burnt

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2
Q

layers of the epidermis from surface to deepest

A
  • Stratum Corneum
  • Stratum Lucidum
  • Stratum Granulosum
  • Stratum Spinosum
  • Stratum Basale
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3
Q

What 2 type of components make up the integumentary system

A
  • Cutaneous membrane

- Accessory Structures

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4
Q

What are the functions of the integumentary system?

A
  • Protection
  • Excretion
  • Maintenance of body temperature
  • Production of Melanin and Keratin
  • Synthesis of Vitamin D
  • Sensation of touch, pressure, temp and pain
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5
Q

What 3 layers make up the cutaneous membrane?

A
  • Epidermis
  • Dermis
  • Hypodermis
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6
Q

What are the 2 sublayers in the Dermis?

A
  • Reticular layer

- Papillary layer

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7
Q

Describe the process of regeneration of Epidermis

A
  • Basal Keratinocytes divide in Stratum Basale
  • Keratinocytes become shrunken and dehydrated in stratum spinosum
  • Keratin is produced and cells start apoptosis in stratum granulosum
  • Cells are flattened and clear in stratum lucidum
  • Dead flat keratinocytes lacking organelles make up the stratum corneum
  • Cells on the surface shed
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8
Q

what stimulates basal keratinocytes to divide beginning epidermal regeneration?

A
  • Epidermal Growth Factor hormone
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9
Q

How does thick skin compare to thin skin?

A

Thick:

  • Thicker Stratum Corneum, Lucidum and Spinosum
  • Well developed dermal papillae (finger ridges)
  • No hair follicles
  • more sweat glands
  • More Sensory receptors
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10
Q

What is the purpose of melanocytes?

A
  • make and secrete melanin, which shields skin from UV light
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11
Q

where can melanocytes be found?

A

in Stratum Basale

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12
Q

what different pigments are there for skin?

A
  • Carotene - yellowish
  • Melanin - Brown, makes freckles and UV protection
  • Blood - gives pink/blue colouration
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13
Q

What makes up the Papillary layer?

A

Areolar tissue

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14
Q

What makes up the Reticular layer?

A

Fibrous network

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15
Q

Name all the components of the dermis:

A
  • Papillary Layer
  • Reticular layer
  • Blood vessels running in the papillary plexus and cutaneous plexus
  • Sensory receptors
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16
Q

What type of tissue makes up the hypodermis?

A
  • Loose connective tissue, Adipose and Areolar tissue

- Connective fibres are also interwoven with reticular layer of dermis

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17
Q

What is Fascia?

A

The vast network of connective tissues making up the skin

18
Q

Name the 3 layers of Fascia:

A

Top layer: Superficial Fascia, this is the hypodermis
Middle: Deep Fascia, dense connective tissue
Bottom: Subserous Fascia, Areolar tissue between serous membrane and deep fascia

19
Q

Function of hair:

A

Protection, Insulation and sensation

20
Q

List the features of a hair:

A
  • Hair
  • Sebaceous gland
  • Connective tissue sheath
  • Root hair plexus
  • arrector pilli muscle
21
Q

what are the 3 layers in a hair stem:

A

Outer - Cuticle, tough thin layer of hard keratin
Middle - Cortex, thick layer of hard keratin
Inner - Medulla, flexible soft keratin

22
Q

What 4 layers make up the hair sheath?

A

Outer - Connective tissue sheath
- Glass membrane
- External root sheath
Inner - Internal root sheath (star shape)

23
Q

Describe Hair Growth:

A
  • Basal Cells in hair matrix (base of cell) fall out
  • Daughter cells are pushed to the surface
  • Follicle becomes inactive and connections between hair root and hair matrix break down
  • Hair falls out, a new hair grows
24
Q

Label a nail:

A
  • Nail body (keratinised cells)
  • Eponychium (cuticle)
  • Lunula (white bit at base)
25
What is the job of the sebaceous gland?
To secrete Sebum
26
How does the sebaceous gland work?
Basal cells divide in the gland and the cell content is then squeezed out into the lumen
27
What 2 types of sweat glands are there?
- Apocrine | - Merocrine
28
Describe how the Apocrine sweat gland works and where:
- Secretes a thick fluid into the hair follicles of the pubic region - Pinches off part of the cell cytoplasm
29
Describe how the Merocrine sweat gland works and where:
- Discharges watery fluid onto skin surface | - Exocytosis of vesicles
30
What does metastasise mean?
spread
31
what types of skin cancer can you get?
78% basal cell carcinomas | 2% malignant melanoma which is likely to spread
32
Describe a first degree burn:
- only affects epidermis | - Causes reddening
33
Describe a second degree burn:
- affects dermis and epidermis | - Causes blistering and scar tissue
34
Describe a third degree burn
- affects epidermis, dermis and hypodermis | - Destroys nerves, and disrupts thermoregulation and infection protection
35
Describe the body process of repairing an injury such as a deep cut:
- Blood fills the cut and mast cells trigger an inflammatory response - The blood clots as fibrin forms a meshy fibrous network. Cells of the stratum Basale migrate along wound perimeters. Phagocytes remove any debris and fibroblasts arrive and build fibre - A thicker fibrous layer forms below the wound and developes upwards with the stratum basale - The scab sheds leaving a shallow depression, fibroblasts continue making scar tissue to reduce the depression
36
what is different about scar tissue from normal tissue?
Scar tissue contains mostly collagen and fewer accessory structures like hair follicles
37
What is an intrinsic factor of skin aging?
- reduction in cell activity - reduction in growth factors - reduction in immune sensitivity
38
What effects do intrinsic factors have on skin?
- Dermal thinning - Wrinkling - White hair - Increased risk of infection
39
What is an extrinsic factor of skin aging?
- Sunshine exposure | - Smoking
40
What effects do extrinsic factors have on skin?
- Increased wrinkling | - Skin cancer