Integumentary System Flashcards
The epidermis is a (structure)
Stratified squamous epithelium
The epidermis is - which means it absorbs nutrients from the basal layer
Avascular
Cells with the highest metabolic demands in the dermis are found near the
Basal lamina
Most abundant epithelial cells
Keratinocytes
Number of strata on thin skin
4 strata
First Strata layer
Stratum basale
- deepest, basal layer
- attached to basement membrane
- contains basal cells (stem cells), melanocytes and tactile cells
Strata second layer
Stratum spinosum
-keratinocytes bound together by desmesomes
Strata third layer
Stratum granulosum
- keratinocytes produce keratohyline and keratin
- keratin fibers form as cells become thinner and flatter
- gradually the plasma membrane thickens, organelles disintegrate and cells die
Fourth layer of strata
Stratum lucidum
-appears as glassy layer in thick skin only
Top layer strata
Stratum Corneum
- many layer of flat dead keratinocytes
- water resistant
- allows slow water loss thru insensible perspiration
Cutaneous membrane parts
Epidermis - superficial epithelium
dermis - underlying connective tissue
Accessory structures
hair, nails, multicellular exocrine glands
hypodermis is the _______ layer that separates:
sub-cutaneous layer that separates integument from deeper layer tissues
Major functions of the integumentary system
PROTECTION of underlying tissues
EXCRETION of organic waste, salts and water via ducts/glands
MAINTENANCE of normal body temp via insulation or evaporation
PRODUCTION of melanin which protects against UV
PRODUCTION of keratin which repels water/ protects from abrasion
SYNTHESIS of vitamin D3 used for calcium metabolism
STORAGE of Lipids in adipose cells and tissue
DETECTION of touch, pain, pressure and temperature
langerhans Cells (AKA…)
Dendritic Cells
Function in immune response against bacteria or superficial skin cancers
Basic component of hair and nails
Keratin
cell death results from
accumulation of keratin causes cells to flatten; lose permeability; distance from dermal blood supply
Name of (5th) strata in thick skin / defining characteristic
stratum lucidum (clear skin)
no organelles in cells - just packed with Keratin
stratum corneum is..
resistant to water
Loss of 500mL of water per day through…. which…
insensible perspiration; can’t be felt
Blister
accumulation of water (insensible perspiration) that accumulates between deep layer and superficial layer of epidermis
Pigments in epidermis
Carotene and melanin