Insulin

Question 0

Exanatide/Byetta

Answer 0

injectable synthetic extendin-4

increases insulin secretion in the presence of increased blood glucose

Question 1

Pramlintide/Symlin

Answer 1

injectable synthetic form of amylin
used by type 1 and two
allows pts to use less insulin
helps avoid postprandial spike
can not use in same syringe as insulin

Question 2

insulin

Answer 2

no activity as an oral agent (can’t survive proteolytic enzymes)
SQ, IM, IV
sides: wt gain, hypoglycemia, hypokalemia,
fibrotic injection sites
muscle or fat atrophy at injection site

Question 3

Exubera

Answer 3

nasal insulin that got withdrawn

Question 4

Rapid acting insulin

Answer 4

lispro/Aspart

Itumulog/Novalog

Question 5

Rapid acting insulin time table

Answer 5

Onset in 15 mins
Peak in 30 mins to 1.5 hrs
Duration 3-5 hrs

Question 6

Short-acting insulin

Answer 6

Regular (humulin R)

Question 7

short acting insulin time table

Answer 7

onset 30 minutes
peak in 2- 4 hours
duration 4-12 hours

Question 8

Intermediate insulin

Answer 8

NPH (humulin R)

Question 9

Intermediate insulin time table

Answer 9

Onset 1-3 hours
Peak 6-12 hours
duration 24-48 hours

Question 10

Long acting insulin

Answer 10

Glargine (lantus)

Question 11

Long-acting insulin time table

Answer 11

onset 4-6 hours
doesn’t peak
duration 24 hours

Question 12

Insulin dosing

Answer 12

Combo of NPH and regular insulin before breakfast and before dinner

Regular insulin before meals and NPH in afternoon