Innate Immunity

Question 1

Innate immunity of comprised of (4)

Answer 1

External barriers
Soluble mediators
Cells
Receptors to detect pathogen

Question 2

Interferon function

chemokines function

Answer 2

Antiviral protection

cell recruitment

Question 3

Innate immunity is (4)

Answer 3

Fast
First
No memory
non-specific

Question 4

What are the functions of innate immunity (3)

Answer 4

Prevent and limit infection in host
Kills microbes
Stimulates and directs adaptive immunity

Question 5

Acute phase proteins are —- derived proteins that are — very early after infection is presented
They are triggered by inflammatory —
They Help mediate —-

Answer 5

Liver
elevated
cytokines
inflammation

Question 6

Inflammation overview:

1. ) Tissue injury releases…
2. ) Dilation and increased —- of —-
3. ) Pathogens are destroyed by —

Answer 6

chemical signals
permeability
capillary
phagocytosis

Question 7

Cytotoxic cells kill target via release of –/—

Name 2 cytotoxic cells.

Answer 7

toxic granules
Eosinophils
neutrophils

Question 8

Phagocytes function (3)

Answer 8

Engulf
Internalise
Destroy

Question 9

During phagocytosis, —- form around the —, Enzyme filled — fuse to form a —–. Fragments are either — or —

Answer 9

Phagosomes
microbe
lysosomes
phagolysosome
presented
exocytosed

Question 10

B cells are primed for innate immunity by…

Th1 cell differentiation needs…

Answer 10

activated complement

pro-inflammatory cytokines