Antigen Presentation

Question 1

CD4 T helper cells recognise — by antigen — cell on the —

Answer 1

antigen
presenting
MHC II

Question 2

CD8 T — cells recognise antigen presented by any — cells on —

Answer 2

cytotoxic
nucleated
MHC 1

Question 3

MHC I+II are assembled in the

Answer 3

Endoplasmic reticulum

Question 4

MHC I loads — antigens via the — pathway using — and chaperone proteins inside the —

Answer 4

exogenous
cytosolic
TAP
Endoplasmic reticulum

Question 5

MHC II loads exogenous — via the — pathway

Answer 5

anitgens

endocytic

Question 6

Endogenous Antigens:
This is the — mediated infection of a cell
It Hijaks the cells machinery for making —
peptides are loaded on MHC class I in the —
MHCI/Ag are trafficked to cell surface in —

Answer 6

receptor
proteins
endoplasmic reticulum
vesicles

Question 7

Exogenous antigens:
Taken up by — or receptor-mediated —
They are processed in acidic — into short —
Peptides are loaded onto pre-formed — into — vesicles
MHCii/Ag is trafficked to cell surface and presented to T cells by —

Answer 7

phagocytosis
endocytosis
vesicles
peptide chains
MHC II molecules
cytoplasmic
APC

Question 8

Exogenous antigens are taken up in vesicles called —

Lysosomes contain acid + — enzymes to aid in —

Answer 8

endosomes
lytic
digestion