Inflammation

Question 1

Inflammation is the response to (2)

Answer 1

Tissue injury or infection

Question 2

What is the purpose of inflammation?

Answer 2

To move immune cells and molecules from blood into the tissue

Question 3

The resulting change in blood vessels and blood flow give rise to the…

Answer 3

Cardinal signs of inflammation

Question 4

Inflammation triggers are conserved structures on — microbes or released from — cells

Answer 4

pathogenic

damaged

Question 5

Soluble mediators increase vascular —

They also increase activation and — of —

Answer 5

permeability
migration
leukocytes

Question 6

Vascular Changes:
Blood cell walls are activated, endothelial cells express –
leukocytes roll, bind and tether using —
Tight junctions between cells become more —
Vasoactive — increase — permeability
cells squeeze between endothelial cells by —
Cells — into tissue
cells move towards chemical gradients or —

Answer 6

adhesins
integrins
permeable
amines
vessel
diapedesis 
extravasate 
chemokines

Question 7

Inflammation overview:

1. ) Tissue inflammation
2. ) Soluble —
3. ) Vascular changes (2)
4. ) Cell recruitment (3 cells)
5. ) effector cells (2)

Answer 7

mediators
permeability
adhesion
monocyte
neutrophil
lymphocytes
phagocytes
lymphocytes

Question 8

Inflammation is switched off by — mediators and removal of — using —

Answer 8

anti-inflammatory
antigens
effector cells

Question 9

Cell recruitment is enhanced by activation of – macrophages near small —/—

Answer 9

tissue

blood vessels