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anp 300 course 2 > innate immune system > Flashcards

innate immune system Flashcards

1
Q

innate immunity includes what?

A

physical and chemical barriers from skin and mucous membranes

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2
Q

What is the first line of defense?

A

Skin and mucous membranes

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3
Q

How cilia is a line of defense?

A

move particles up to throat

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4
Q

How lacrimal apparatus defends?

A

washes away from eyes

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5
Q

What lysozymes do?

A

break down cell walls of bacteria

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6
Q

what saliva does?

A

washes microbes from teeth and mouth

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7
Q

How second line of defense works?

A

defend against anything that gets past first line

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8
Q

What are phagocytes

second line of defense

A

ingest microbes and other particles

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9
Q

Two major types of phagocytes

A

neutrophils and macrophages

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10
Q

Neutrophils do what?

A

Most abundant and phagocytize debris/bacteria

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11
Q

Two types of macrophages

A

Fixed
Free

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12
Q

What dendritic cells do?

A

Found in tissue contacting outside environment

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13
Q

What eosinophils do

less abundant than neutrophils

A

phagocytize foreign compunds

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14
Q

1st step of phagocytosis?

A

Chemotaxis
movement of phagocyte due to attraction to chemicals

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15
Q

Second step of phagocytosis

A

Adherance

attachment to target cell

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16
Q

3rd step of phagocytosis

A

Ingestion

False feet form and engulf target cell

17
Q

4th step of phagocytosis

A

Digestion

lysozymes, etc.. bind with phagosome

18
Q

5th step of phagocytosis

A

Killing

death of target cell, release of debris

19
Q

1st step of NK recognition and destruction

A

Recognition and adhesion to target cell

20
Q

2nd step of NK recognition and destruction

A

Golgi apparatus aligns and creates perforins

21
Q

3rd step of NK recognition and destruction

A

Perforins released and arrive at target

22
Q

4th step of NK recognition and destruction

A

perforins create pores and cell disintegrates

23
Q

What are interferons

A

release antiviral proteins which interfere with replication

24
Q
A

anp 300 course 2 (18 decks)

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