Inherited Changes Flashcards

1
Q

Define fertilisation

A

When the nucleus of a sperm cell fuses with the nucleus of an ovum
Resulting in a zygote which has 46 chromosomes

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2
Q

How are the 46 chromosomes in your body divided up

A

22 pairs of chromosomes and one pair of sex chromosomes

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3
Q

What is an allele

A

Alternating forms of the same gene

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4
Q

Where are homologous pairs for same characteristics found

A

At the same loci

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5
Q

What is mono hybrid inheritance

A

Inheritance of a single gene

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6
Q

What is dihybrid inheritance

A

Investigating two characteristics at the same time

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7
Q

What is the expected ratio for a dihybrid cross

A

9:3:3:1

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8
Q

What is co dominance

A

Both alleles are dominant and both are expressed in the phenotype

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9
Q

How do you write a co dominant cross

A

Using super script letters

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10
Q

Why is sex inheritance different to other types of inheritance

A

Sex is determined by a chromosome not a gene

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11
Q

Explain sex linkage

A

Any gene carried on the X or the Y
There is no equivalent homologous portion on the Y chromosome and most of the alleles are recessive

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12
Q

Which gender are characteristics more likely to appear in

A

Males because the X chromosome is much longer than the Y
There is no equivalent homologous portion of the Y so recessive characteristics on the X appear in phenotype

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13
Q

Why is haemophilia almost always inherited by the mother

A

Faulty allele carried on X chromosome
No equivalent region of Y chromosome
Males always inherit X chromosome from the mother

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14
Q

What is an autosome

A

The other 22 chromosomes that aren’t sex linked

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15
Q

What is autosomal linkage

A

Two genes are on the same chromosome at the same loci and gametes aren’t produced equally
they are likely to be inherited together
No independent segregation

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16
Q

What is epistasis

A

When the allele of one gene effects or masks the expression of another gene in the phenotype

17
Q

Expected ratio in epistasis

A

9:3:4

18
Q

Why may differences in the expected and observed ratios happen

A

Due to chance = random fertilisation
Not due to chance = autosomal linkage
Epistasis
Lethal genotypes
Some genotypes are more or less likely to survive - natural selection