DNA genes and chromosomes Flashcards

1
Q

what is the difference between a chromosome and chromatid

A

chromatids are half of a chromosome
they contain the same genetic material

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2
Q

what is a homologous chromosome

A

chromosome pairs with the same centromere position one from mother and one from father
but they are genetically different

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3
Q

describe how DNA is wound into a chromosome

A

DNA double helix is wound around a histone and the complex then coils.
this coil is further coiled and packaged into a chromosome.

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4
Q

what is the haploid number

A

23

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5
Q

what is the diploid number

A

46

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6
Q

what is an allele

A

version of a gene

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7
Q

what is a phenotype

A

physical expression of a gene

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8
Q

what is a genotype

A

genes you contain

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9
Q

why do we have a triplet code

A

so that we have enough combinations to code for each amino acid

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10
Q

what is a locus

A

the place a particular section of DNA is located

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11
Q

what does the base sequence of each gene contain

A

amino acid sequence in a polypeptide
functional RNA , ribosomal RNA and transfer RNA

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12
Q

what is an intron

A

non coding DNA

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13
Q

what is an exon

A

coding DNA

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14
Q

what are the bonds between base pairs

A

hydrogen

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15
Q

what are the bonds between base pairs and backbone

A

phosphodiester

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16
Q

what are the bonds between amino acids

A

peptide bonds

17
Q

where are triplet codes found

18
Q

where are codons found

19
Q

where are anticodons found

A

TRNA / proteins

20
Q

what does degenerate mean

A

amino acids have more than one triplet code

21
Q

what does universal mean

A

the same triplet of DNA bases are for the same amino acids in all organisums

22
Q

what does non overlapping mean

A

each DNA base in each triplet is only read once

23
Q

what do genes code for

A

ribosomal RNA and transfer RNA

24
Q

are introns and exons found in prokaryotic cells

A

only exons

25
what is transcription
production of MRNA using a DNA template. A gene is transcribed into an MRNA molecule
26
what is translation
the production of polypeptides using the sequence of codons carried by MRNA occurs in a ribosome
27
describe transcription
DNA helicase unwinds sections of DNA ro expose the bases by breaking hydrogen bonds RNA polymerase attaches to the exposed polynucleotide and joins complementary RNA nucleotides together forming pre MRNA Pre MRNA is is then spliced to form MRNA which diffuses out of the nucleus
28
what is splicing
removing introns from pre MRNA allowing different proteins to be made
29
similarities of transcription and DNA synthesis
DNA helicase is used phosphodiester bonds are made use complementary base pairs
30
differences of transcription and DNA synthesis
RNA polymerase in transcription instead of DNA polymerase Pre MRNA is formed in transcription whilst DNA synthesis produces two DNA molecules splicing is required in transcription but not in DNA synthesis DNA synthesis does the whole chromosome transcription is just one gene
31
what does TRNA do
it had an amino acid attachment site and an anticodon loop consisting of 3 unpaired bases making TRNA specific to each amino acid
32
why do amino acids need ATP in TRNA
so that it is activated to be picked up by TRNA
33
describe translation
MRNA associates with ribosomes in the cytoplasm the first two codons are on the ribosome and attract their complementary TRNA anticodons of the TRNA join via complementary base pairing forming hydrogen bonds with MRNA codons peptide bonds are formed ribosome moves onto the next codon the first TRNA leaves the ribosome and a new one enters another peptide bond is formed between the second amino acid and the new one this continues until the ribosome reaches a stop codon
34
what does transferase do
creates peptide bonds between amino acids and breaks bonds from TRNA
35
what does a stop codon do
codes for a release factor not an amino acid