Inhalation Agents & MAC - Quiz 10 Flashcards
The lower the MAC the ______ potent the inhaled agent
The lower the MAC the more potent the inhaled agent
What is MAC-Amnesia?
25% MAC
Concentration that blocks anterograde memory in 50% of awake patients
What is MAC-Awake
50% MAC
Concentration needed to prevent eye opening on verbal command
What is MAC-Intubation?
130% MAC
Concentration needed to prevent movement & coughing during intubation
What is MAC-BAR?
150% MAC
Concentration needed to block autonomic/adrenergic response to incision
What factors Increase MAC?
Babies < 6 months old - highest MAC needed
Chronic EtOH
Hyperthermia
Hypernatremia
Drugs that Increase Catecholamines
What factors Decrease MAC?
- Pregnancy
- Hypothermia
- Hypoxemia
- Premature Babies & Elderly
- Acute ETOH
- Hyponatremia
- Lithium
- Alpha 2 Agonist/C-Channel Blockers
- Bypass Machine
How much does MAC decrease for every drop in degree of body temperature?
Every 1 degree Celsius drop = 2-5% Decrease in MAC
What factors have ZERO effect on MAC?
Thyroid Problems
Duration of Anesthesia
Gender
Potassium Level
CO2 Level???
What is the MAC % of Halothane?
0.75 %
What is the MAC % of Isoflurane?
1.15 %
What is the MAC % of Enflurane?
1.68 %
What is the MAC % of Sevoflurane?
2 %
What is the MAC % of Desflurane?
6 %
What is the MAC % of N2O?
105 %
How does a high Inspired Concentration affect Induction?
Speeds Indunction d/t Concentration Effect
What does Increased Alveolar Ventilation effect Induction?
Increased Ventilation speeds Induction
What factors are invovled in the Uptake of gas from Alveolar Space?
Gas Solubility
Cardiac Output
Alveolar/Venous Partial Pressure Difference
What is the most important single factor in determining Induction Speed & Emergence Rate?
Solubility (Blood:Gas Partition Coefficient)
What is the Blood:Gas for Desflurane?
0.42