Hemodynamics and Hemodynamic Measurements - Quiz 4 Flashcards
How to measure Blood Flow
Velocity x Cross Sectional Area
In Ohm’s Law, what 2 factors determine blood flow through a vessel?
1) Difference in Pressure
2) Resistance
Flow (Q) = (PA - PV) / R
What is Blood Pressure
The force exerted by blood against the vessel wall
1 mmHg = ? cm-H2O
1 mmHg = 1.36 cm-H2O
What is Cerebral Perfusion Pressure
Cerebral Perfusion Pressure = MAP - CVP or ICP (whichever higher)
What has greatest impact on rate of bloow flow through a vessel wall regarding Poiseuille’s Law?
Diameter of Blood Vessel
What is Resistance
The impediment of blood flow in a vessel - cannot be directly measured
SVR Formula
SVR = [(MAP - CVP) / CO] X 80
Normal: 700-1600
PVR Formula
PVR = [(MPAP - PCWP) / CO] x 80
Normal: 100 - 300
Calculating resistance in blood vessels arranged in a series
Total Resistance = Sum of Resistance of Each Vessel
Rt = R1 + R2 + R3 + R4
Calculating blood vessel resistance in Parallel Arrangement?
1/Rt = 1/R1 + 1/R2 + 1/R3
Paralell Arrangement allows for Local Blood Flow Regulation
What happens to total resistance if you added another blood vessel in a parallel arrangement?
Total resistance would decreases - another channel for blood to flow through
What is Laminar Flow
Fluid particles following moving in smooth paths in layers in a parallel
What is Turbulent flow?
Turbulent flow occurs when it fluids make sharp turn or passes over rough surface, becoming disorderly.
Blood flows crosswise in vessel and form local eddies, increasing flow resistance due to friction.
Formula used to predict laminar vs turbulent flow
Reynold’s Number (NR)
NR = pDv / n
p = density D = tube diameter v = velocity n = viscosity
Relationship of Hematocrit to Blood Viscosity?
Increasing Hematocrit increases Viscosity
Why does an increase in Blood Pressure cause a much greater increase in Blood Flow
As opposed to the arterial blood flow, an increase in venous blood pressure increases flow because the vessels become more rounded and lowers resistance –> increases venous return.
What is the mechanism that drives blood flow?
The difference in total energy between two points
What are the three primary factors that determine blood flow resistance in a single vessel?
- Vessel Diameter - most important
- Vessel Length
- Viscosity of Blood
Vessel resistance is ______ proportional to vessel length and blood viscosity
Directly Proportional
Vessel Resistance is _______ proportional to the radius to the fourth power
Inversely proportional
What is the basis of Bernoulli’s Principle?
Kinetic Energy and Pressure Energy can be interconverted so that total energy remains the same.