Inflammation and wound healing (E1)

Question 1

First line of defense

Answer 1

non specific and not activates/ deactivated

Question 2

second line of defense

Answer 2

non-specific, activated as needed. Inflammation with non specific white blood cells

Question 3

third line of defense

Answer 3

specific immunity, activated as needed. with T- cells and b- cells

Question 4

what is inflammation

Answer 4

a non-specific localized response to injury

Question 5

clinical manifestation of inflammation

Answer 5

pain, redness, swelling, heat, temporary loss of function

Question 6

exudate

Answer 6

fluid that flows in a area of irritation, causes swelling

Question 7

serous exudate

Answer 7

fluid inside blisters (clear)

Question 8

fibrinous exudate

Answer 8

cloudiness in fluid

Question 9

purulent exudate

Answer 9

abscess full of pus

Question 10

hemorrhagic exudate

Answer 10

blood into area of inflammation

Question 11

granulomas

Answer 11

can form with inflammation, encapsulates pathogen or foreign object

Question 12

what happened during an inflammatory response (chemical)

Answer 12

degranulation of mast cells which releases histamine, WBC chemotactic factors, and long term response chemicals

Question 13

Histamine

Answer 13

stored in cytoplasmic granules, a vasodilator

Question 14

white blood cells chemotactic factors

Answer 14

attract wbcs to areas

Question 15

Long term inflammatory chemical response

Answer 15

prostaglandins and leukotrienes. Maintain rather than initiate inflammation

Question 16

complement system

Answer 16

plasmas proteins that target foreign invaders

Question 17

clotting system

Answer 17

coagulation, increases blood clotting

Question 18

Inflammation phases

Answer 18

vasodilation, phagocyte migration, repair

Question 19

vasodilation

Answer 19

blood vessels get wider with an increases in tissue permeability and an influx of exudate

Question 20

margination and pavementing

Answer 20

WBC sense chemotactic factors and stick against blood vessel wall

Question 21

diapedesis

Answer 21

phagocytes squeeze between blood vessel/ tissue cells to reach where chemotactic factor is strongest

Question 22

regeneration (tissue)

Answer 22

made as it was before including structure and function

Question 23

repair (tissue)

Answer 23

with more extensive
damage, scar tissue that may mean not all structure or function returned

Question 24

reconstructive (tissue)

Answer 24

happens first, focuses on rebuilding, adding cells, and actual structure

Question 25

maturation (tissue)

Answer 25

restoring function of tissue

Question 26

Primary repair of tissue

Answer 26

regenerative wound, not as serious

Question 27

secondary tissue repair

Answer 27

more likely to cause scar tissue accumulation

Question 28

dysfunction in inflammation/wound healing

Answer 28

hypovolemia, defects in collagen synthesis, dehiscence, wound contracture

Question 29

hypovolemia (wound healing)

Answer 29

vessel constriction

Question 30

hypertrophic scarring

Answer 30

defect in collagen synthesis, overdevelopment of tissue in area of scarring, keloid

Question 31

dehiscence

Answer 31

reopening of sutured wounds

Question 32

wound contracture

Answer 32

scar collapsing in on itself