Infectious Diseases - Antibiotics: bactericidal vs bacteristatic and time vs concentration Flashcards

1
Q

Which antibiotics are BacteriCIDAL

A

Vancomycin

Fluoroquinolones

Penicillin

Aminoglycosides

Cephalosporins

Metronidazole

** Very Finely Proficient At Cell Murder **

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2
Q

Which antibiotics are Bacteristatic Antibiotics (inhibit bacterial growth)

A

Erythromycin

Clindamycin

Sulfamethoxazole

Trimethoprim

Tetracyclines

Chloramphenicol

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3
Q

Vancomycin - bacteriocidal or bacteristatic?

A

Bactericidal

Remember: 
** Very Finely Proficient At Cell Murder **
Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Cephalosporins
Metronidazole
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4
Q

Erythromycin - bacteriocidal or bacteristatic?

A

Bacteristatic

** Remember: 
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracyclines
Chloramphenicol
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5
Q

Fluoroquinolones - bacteriocidal or bacteristatic?

A

Bactericidal

Remember: 
** Very Finely Proficient At Cell Murder **
Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Cephalosporins
Metronidazole
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6
Q

Clindamycin - bacteriocidal or bacteristatic?

A

Bacteristatic

** Remember: 
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracyclines
Chloramphenicol
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7
Q

Trimethoprim - bacteriocidal or bacteristatic?

A

Bacteristatic

** Remember: 
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracyclines
Chloramphenicol
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8
Q

Penicillin - bacteriocidal or bacteristatic?

A

Bactericidal

Remember: 
** Very Finely Proficient At Cell Murder **
Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Cephalosporins
Metronidazole
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9
Q

Aminoglycosides - bacteriocidal or bacteristatic?

A

Bactericidal

Remember: 
** Very Finely Proficient At Cell Murder **
Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Cephalosporins
Metronidazole
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10
Q

Sulfamethoxazole - bacteriocidal or bacteristatic?

A

Bacteristatic

** Remember: 
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracyclines
Chloramphenicol
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11
Q

Cephalosporins - bacteriocidal or bacteristatic?

A

Bactericidal

Remember: 
** Very Finely Proficient At Cell Murder **
Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Cephalosporins
Metronidazole
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12
Q

Metronidazole - bacteriocidal or bacteristatic?

A

Bactericidal

Remember: 
** Very Finely Proficient At Cell Murder **
Vancomycin
Fluoroquinolones
Penicillin
Aminoglycosides
Cephalosporins
Metronidazole
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13
Q

Tetracyclines - bacteriocidal or bacteristatic?

A

Bacteristatic

** Remember: 
Erythromycin
Clindamycin
Sulfamethoxazole
Trimethoprim
Tetracyclines
Chloramphenicol
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14
Q

Which antibiotics are TIME dependent (and what does that mean?)

A

= outcome predicted by T>MIC or can use AUC/MIC

Beta-lactams

Vancomycin

Macrolides

Aztreonam

Carbapenams

Clindamycin

Tetracycline

Azoles

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15
Q

Which antibiotics are CONCENTRATION dependent (and what does that mean)?

A

= outcome predicted by peak/MIC

Fluoroquinolones

Aminoglycosides

Amphotericin B

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16
Q

What does time dependent antibiotic mean?

A

= outcome predicted by T>MIC or can use AUC/MIC

17
Q

What does CONCENTRATION dependent antibiotic mean?

A

= outcome predicted by peak/MIC

18
Q

Vancomycin - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC

19
Q

Macrolides - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC

20
Q

Fluoroquinolones - Time or Concentration Dependent

A

CONCENTRATION dependent

= outcome predicted by peak/MIC

21
Q

Aztreonam - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC

22
Q

Aminoglycosides - Time or Concentration Dependent

A

CONCENTRATION dependent

= outcome predicted by peak/MIC

23
Q

Carbapenems - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC

24
Q

Azoles - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC

25
Q

Amphotericin B - Time or Concentration Dependent?

A

CONCENTRATION dependent

=outcome predicted by peak/MIC

26
Q

Clindamycin - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC

27
Q

Tetracyclines - Time or Concentration Dependent

A

TIME dependent

=outcome predicted by T>MIC or can use AUC/MIC