Infectious Disease Pharmacology

Question 1

Gram positive bacteria – treponema pallidum (Syphilis)

Answer 1

Penicillin G and Penicillin V

Question 2

MSSA (Methicillin-sensitive Staphylococcus aureus)

Answer 2

Nafcillin, Oxacillin, and Dicloxacillin

Question 3

Gram positive and gram negative bacteria – streptococcus, enterococcus, haemophilus, helicobacter, moraxella, some strains of e. coli, proteus mirabilis, and shigella

Answer 3

Ampicillin and Amoxicillin

Question 4

Aerobic gram positive, gram negative bacteria, and anaerobic bacteria (not c diff), pseudomonas aeruginosa, neutropenic fever

Answer 4

Piperacillin and ticarcillin

Question 5

MSSA and streptococcus

Answer 5

First generation cephalosporin

Question 6

Increased gram negative bacilli coverage and decreased gram positive coverage, PID

Answer 6

Second generation cephalosporin

Question 7

Meningitis, PNA, neutropenic fever, epiglottitis, spontaneous bacterial peritonitis, gonorrhea, and pyelonephritis

Answer 7

3rd generation cephalosporin

Question 8

Increased pseudomonal activity with the same level of efficacy for gram positive bacteria as the 1st generation cephalosporins

Answer 8

4th generation cephalosporin

Question 9

Multidrug resistant infection and bacteria with extended spectrum beta lactamases

Answer 9

Carbapenem

Question 10

Gram positive infection, MRSA, C Diff (after metronidazole), and endocarditis

Answer 10

Vancomycin

Question 11

URI, chlamydia, gastroenteritis, mycobacterium avium complex, and campylobacter

Answer 11

Macrolide

Question 12

Gram positive infection, staph (MSSA and MRSA), strep (including toxic shock and necrotizing fasciitis), and anaerobes (respiratory and pelvic infections)

Answer 12

Clindamycin

Question 13

MRSA, streptococci, vancomycin resistant staph, vancomycin resistant enterococci, and multi drug resistant gram positive bacteria

Answer 13

Linezolid

Question 14

Aerobic negative bacteria, sepsis, PNA, nosocomial respiratory infection, endocarditis, intra abdominal infections, osteomyelitis, and complicated UTIs

Answer 14

Gentamicin, tobramycin, and amikacin

Question 15

Chlamydia, PID, RMSF, MRSA, Lyme, anthrax, CAP, malaria, syphilis

Answer 15

Doxycycline

Question 16

Acne

Answer 16

Minocycline

Question 17

Quadruple therapy for H pylori

Answer 17

Tetracycline

Question 18

MRSA, gram negative bacili, strep, anaerobes, PNA, and vancomycin resistant organisms

Answer 18

Tigecycline

Question 19

CAP (not cipro), complicated cystitis, pyelonephritis, puncture wounds, gram negative bacili, osteomyelitis, gastroenteritis, and anthrax

Answer 19

Fluoroquinolones

Question 20

Pneumocystis prophylaxis (CD4 count <200), MRSA, cystitis, and pyselonephritis

Answer 20

Trimethoprim/Sulfamethoxazole

Question 21

HSV-1, HSV-2, varicella, herpes zoster, herpes encephalitis (acyclovir can be given IV), and Bells palsy

Answer 21

Acyclovir, valacyclovir, famciclovir

Question 22

Chronic hepatitis C

Answer 22

Ledipasvir, Sofosbuvir

Question 23

Tuberculosis

Answer 23

Rifampin
Isoniazid
Pyrazinamide
Ethambutol