infections in pregnancy Flashcards
chicken pox symptoms
fever
malaise
vesicular rash
chicken pox period of infectivity
48hrs before onset rash until lesions have crusted over
usually 5-7days
chicken pox and pregnancy risks
pregnant women at risk of more severe disease (immunocompromised)
small risk congenital infection in first 28wks
if infected last 4wks pregnancy risk infection in newborn
advise avoid exposure and seek medical advice if do
chicken pox: pregnant woman exposed
check immune status - serum IgG
if immune reassure
if no immunity give varicella zoster Ig ASAP
pregnant women gets chicken pox: what to do if mild infection and <24hrs since rash onset
oral aciclovir
if >20wks
consider if <20wks
pregnant women gets chicken pox: what to do if mild infection and >24hrs since rash onset
aciclovir has no role
symptomatic Rx
hygeine to avoid 2ry bacterial infection
pregnant women gets chicken pox: what to do if severe infection
IV aciclovir
hospital admission
parovirus B19
spread by resp secretions
fever, rash, erythema of cheeks
what can parovirus B19 infection in pregnancy cause
fetal anaemia: cardiac failure, hydrops fetalis, death
maternal eclampsia w significant oedema
if pregnant woman exposed to parovirus B19
check immunity - serum Ig
weekly scans to monitor for complications
parovirus B19 critical exposure period in pregnancy
12-20wks
fetal infection 5wks after maternal infection
toxoplasmosis
protozoa organism toxoplasma gondii
mild-flu like illness: sore throat, arthralgia, coryza, fever
toxoplasmosis severe complications
chorioretinitis
encephalitis
myocarditis
pneumonitis
toxoplasmosis when is placental infection possible
parasitaemia 3wks after ingestion
placental infection possible during pregnancy and immediately prior to pregnancy
pregnant women told to avoid cat litter trays and undercooked meat
toxoplasmosis congenital infection
infection 3rd trimester highest risk
PCR of amniotic fluid can identify toxoplasmosis and confirm congenital infection