bleeding in early pregnancy Flashcards

1
Q

differential diagnoses

A
ectopic 
pregnancy unknown location 
molar pregnancy 
early misscarriage
threatened misscarriage
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2
Q

risks for ectopic pregnancy

A
previous ectopic 
fallopian tube pathology 
PID
endometriosis
IUD
assisted reproduction 
age >35
smoker
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3
Q

when to have medical management ectopic

A

patient stable
ectopic <3cm
no fetal heart beat seen

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4
Q

medical management ectopic

A

methotrexate injection and follow up

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5
Q

what is used to monitor response to methotrexate therapy

A

serial B-HCG measurements

checked every week until <20

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6
Q

pregnancy of unkown location

A

positive UPT but unknown location

too early to see either intrauterine/ectopic pregnancy

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7
Q

PUL what helps guide management

A

US and sr BHCG

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8
Q

molar pregnancies

A

placenta is abnormal and pregnancy does not develop properly

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9
Q

complete moles

A

no evidence of fetal tissue

consequence of duplication of a single sperm following fertilisation of an ‘empty’ ovum

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10
Q

partial mole

A

2 sets of paternal haploid genes and one set of maternal haploid genes
dispermic fertilisation of ovum

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11
Q

molar pregnancy treatment

A

suction curettage

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12
Q

misscarriage

A

loss of pregnancy diganosed by symptoms of heavy bleeding and passing fetal tissue/scan findings before 24wks

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13
Q

threatened misscarriage

A

vaginal bleeding +/- pain
viable pregnancy
closed cervix

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14
Q

inevitable miscarriage

A

viable pregnancy

open cervix with bleeding that could be heavy

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15
Q

expectant management of miscarriage

A

for 7-14days following confirmed diagnosis of non-viable pregnancy

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16
Q

surgical management of misscarriage

A

manual vacuum apsiration under local anaesthetic/evacuation in theatre under GA

17
Q

medical management of miscarriage

A

misoprostol (prostaglandin E2)

18
Q

presentation of septic misscarriage

A

febrile
tender uterus/abdomen
bleeding
smelly discharge

19
Q

septic miscarriage management

A

broad spectrum antib e.g. co-amoxiclav

uterine evacuation

20
Q

recurrent misscarriage

A

3+ consecutive spontaneous miscarriage
1ry - no prev successful pregnancy
2ry - prev successful pregnancy

21
Q

risks for recurrent misscarriage

A
smoking 
anti-phospholipid syndrome 
genetic
anatomical abnormalities
infection