Infection & Response- Monoclonal Antibodies

Question 1

__________ antibodies are produced from a ______ cell clone.

Answer 1

Monoclonal antibodies are produced from a single cell clone.

Question 2

Monoclonal antibodies specifically ____ onto one shape of _______, so can target
one type of ____ or ________ inside the body.

Answer 2

Monoclonal antibodies specifically bind onto one shape of antigen, so can target
one type of cell or chemical inside the body.

Question 3

Monoclonal antibodies are made using mouse l__________ and t_____ cells to
make a h________ cells.

Answer 3

Monoclonal antibodies are made using mouse lymphocytes and tumour cells to
make a hybridoma cells.

Question 4

H________ cells are _____ to produce the same ________ that can be collected
and ________.

Answer 4

Hybridoma cells are cloned to produce the same antibody that can be collected
and purified.

Question 5

Monoclonal antibody uses include: _________ _____, locating specific _____ or _______
and ______ treatments.

Answer 5

Monoclonal antibody uses include: pregnancy tests, locating specific cells or tissues
and cancer treatments.

Question 6

what are the advantages of monoclonal antibodies?

Answer 6

• they only bind to the specific diseased or damaged cells that need treatment
• the specificity of monoclonal antibodies means they can be used to treat a wide rage of conditions
• healthy cells are not affected

Question 7

what are the disadvantages of monoclonal antibodies?

Answer 7

• expensive
• has many side effects