Infectii nespecifice maxialre si Osteonecroza maxilare Flashcards

1
Q

De cate feluri sunt osteomielitele?

A
  • O supurata acuta
  • O supurata cronica
  • O nesupurata cronica de tip sclerogen
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Caracteristici generale ale osteomielitei

A
  • ag. patogen=stafilococul venit pe cale hematogena de la distanta
  • cuprinde toate straturile osului (periost-corticala-medulara)
  • mandibula>maxilar (corticala prea densa ce nu permite drenajul)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Aspect oral al Osteomielitei supurate acute:

A
  • mucoasa edematiata, congestiva
  • dinti mobili, cu sensibilitate dureroasa spontana/provocata la percutie, iradiata
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ce se intampla dupa fistulizare la OSA?

A
  • starea gen se remite
  • anestezia labio-mentoniera/infraorbitala persista dupa fistulizare
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Modificari radiologice OSA:

A
  • primele apar dupa ce procesul inflamator din tesutul medular s-a raspandit in tesutul osos
  • expresie rx dupa ce osteoliza ajunge la 50-60%, la 3-4 sapt de la debut
  • alternanta rxtransparenta/rxopace, contur neregulat
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dg diferentia Osteomielita supurata acuta:

A
  1. Osteita periapicala, cu stare gen nemodificata
  2. Infectii periosoase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cum e definita Osteomielita supurata cronica?

A
  • cu o durata de evolutie peste 6 sapt
  • cu recurenta dupa infectia initiala
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Simptome Osteomielita cronica supurata:

A
  • proces lent, putine simptome
  • deformare corticale
  • tulb snezitive
  • fistule tegumentare/mucoase
  • tesut osteitic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Aspect rx al Osteomielitei cronice supurate:

A
  • “capac de sarcofag”
  • sechestru osos opac, delimitat de transparenta cu contur neregulat-focar osteolitic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Evolutie Osteomielita cronica supurata la copii

A
  • la unghi mandibular
  • debut insidios, fara semne evidene
  • rx: zona centrala de radiotransparenta, bordata de reactie periostala
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Dg diferential Osteomielita cronica nesupurata

A
  1. Displazii fibroase
  2. Tumori osoase benigne/maligne
  3. Osteomielite cronice specifice
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Metode tratament Osteomielita cronic supurata:

A
  1. Sechestrectomie
  2. Corticotomie
  3. Extractie dd cauzali si a celor implantati pe sechestre
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ce este Osteomielita nesupurata cronica de tip sclerogen?

A
  • apozitie osoasa subperiostala
  • determinata de un proces infectios odontogen sau de supuratii p. moi supraiacente
  • stafilococi
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Dg diferential Osteomielita cronica nesupurata sclerogena

A
  1. Osteoperiostita
  2. Displazii fibroase
  3. Tumori benigne/maligne osoase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Care e cauza Osteoradionecrozei?

A
  • expunere la radiatii ionizante profund penetrante (in brahiterapie tumori omf)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Care sunt celulele radiosensibile ?

A
  • osteocitele- tulburare turn-over osos+reducere ritm vindecare osoasa
  • celule endoteliu vascular- tulburari circulatorii(tromboze)
17
Q

Ce simptome are osteoradionecroza?

A
  • fara suprainfectie- nu are aucze subiective
  • daca sunt leziuni de osteita/osteomielita- simptome ca in osteomielita supurata
18
Q

Care e tendinta naturala a osteoradionecrozei?

A
  • de formare de sechestre osoase
  • se produc frecvent “fracturi in os patologic”
  • rx nu se vad initial modificari
19
Q

In ce consta profilaxia osteoradionecrozei?

A
  • inlaturare leziuni dento-parodontale
  • ablatie lucrari protetice metalice

pot deveni surse secundare de iradiere

20
Q

Prin ce e caracetizata Osteonecroza maxilarelor asociata medicatiei antiresorbtive/antiangiogenice

A
  • suprafata osoasa expusa in CB
    persista peste 8 saptamani
  • la pacienti fara radioterapie si fara leziuni metastatice la oase maxilarele
21
Q

Care sunt principalele preparate antiresorbtice si antiangiogenice, asociate cu risc de dezvoltare osteonecroza?

A
  1. Antiresorbtive osoase de tip inhibitori de osteoclaste (bifosfonati)
  2. Antiresorbtive osoase de tip anticorpi monoclonali anti-EANKL-(denosumabul)
  3. Antiangiogenice-(bevacizumab)
22
Q

La ce sunt folosite aceste medicatii?

A
  • metastaze osteolitice
  • mielom multiplu
  • osteoporoza
23
Q

Inhibitorii de osteoclaste(bifosfonatii) la cat timp declanseaza afectiunea?

A
  • 3-6 luni- adm parenterala
  • 36 de luni adm orala
24
Q

Ce anume precipita declansarea osteonecrozei?

A

aparitia unei solutii de continuitate la mucoasa orala, dupa interv chirurgicale/stomatologice la pacienti ce urmeaza un tratament cu bifosfonati

25
Q

Etapa 0 a osteonecrozei maxilarelor

A
  • simpt subiectiva redusa
  • dureri nevralgiforme nespecifice
  • rx- osteocondensare la proces alveolar
  • PET-CT/scintigrafiea sugestive, dar nu neaprat necesare
26
Q

Stadiul I, clinic si rx

A
  • Clinic→ os denudat/arii de necroza-limitate la proces alveolar, fara semne de infectie
  • RX→ img nespecifica de liza osoasa la proc alveolar sau resorbtie osoasa fara legatura aprenta de leziuni d-p
27
Q

Stadiul II, clinic si rx

A
  • Clinic→ os denudat/arii necroza limitate la proces alv; cu prezenta semnelor de infectie
  • fistule mucozale cu plecare osaosa sau tegumentara, fara etio d-p
  • tulb sensibilitate fara etio d-p
  • RX→ img nespecifica de liza osoasa la proc alveolar sau resorbtie osoasa fara legatura aprenta de leziuni d-p
28
Q

Stadiul III, clinic si RX

A
  • Clinic→ os denudat/arii necroza, ce se extind dincolo de proces alveolar (ram mand, mg bazilara mand, sinus maxilar*); prezente semne infectie
  • Fistule mucozale cu plecare osoasa/tegumentara
  • Tulb sensibilitate
  • mobilitate dent, fara etio d-p
  • sechestre osoase
  • fractura mandibula in “os patologic”
  • comunicare oro-antrala/oro-nazala
  • RX→ liza dincolo de proces alv*
  • semne de fractura mand
  • semne specifice de sinuzita maxilara odontogena