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Pharmacology > Immunosuppresive drugs > Flashcards

Immunosuppresive drugs Flashcards

1
Q

cytotoxic immunosuppressive drugs

A 
cyclophosphamide, isosfamide
methotrexate
azathioprine, 6-mercaptopurine
leflunomide, teriflunomide
mycophenolate mofetil
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2
Q

calcineurin inhibitors

A

cyclosporine A

Tacrolimus, pimecrolimus

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3
Q

mTOR inhibitors

A

Sirolimus, everolimus, temsirolimus

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4
Q

Janus Kinase (JAK) inhibitors

A

Tofacitinib, Baricitinib

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5
Q

5-aminosalicylic-acid (5-ASA) derivatives

A

Sulphasalazin, mesalazine

Olsalazine balsalazide

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6
Q

1st generation retinoids

A

tretinoin
isotretinoin
alitretinoin

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7
Q

2nd generation retinoids

A

acitretin

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8
Q

3rd generation

A

bexarotene
adaplene
tazarotene

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9
Q

Antibodies against T cells

A

Muromonab-CD3
Basiliximab
Daclizumab

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10
Q

Antibodies against B cells

A

Rituximab
ocrelizumab
Alemtuzumab

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11
Q

Antibodies against TNFalpha

A 
Adalimumab
Certolizumab pegol
etanercept
golimumab
infliximab
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12
Q

IL-1 receptor antagonist

A

Anakinra

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13
Q

Anti IL1 beta

A

canakinumab

rilonacept

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14
Q

anti IL-5

A

reslizumab

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15
Q

anti IL-6

A

tocilizumab

sarilumab

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16
Q

anti IL-17

A

secukinumab
ixekizumab
brodalumab

17
Q

anti IL-12/23

A

ustekinumab

18
Q

anti IL-23

A

Guselkumab

19
Q

Anti B lymphocyte stimulator protein

A

Belimumab

20
Q

antibodies for integrin

A

natalizumab

vedolizumab

21
Q

antibody against complement factor 5

A

eculizumab

22
Q

antibody against FCe part of IgE

A

omalizumab

23
Q

CTLA4-containing fusion protein

A

abatacept

Pharmacology (36 decks)

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