Immunosuppresive drugs

Question 1

cytotoxic immunosuppressive drugs

Answer 1

cyclophosphamide, isosfamide
methotrexate
azathioprine, 6-mercaptopurine
leflunomide, teriflunomide
mycophenolate mofetil

Question 2

calcineurin inhibitors

Answer 2

cyclosporine A

Tacrolimus, pimecrolimus

Question 3

mTOR inhibitors

Answer 3

Sirolimus, everolimus, temsirolimus

Question 4

Janus Kinase (JAK) inhibitors

Answer 4

Tofacitinib, Baricitinib

Question 5

5-aminosalicylic-acid (5-ASA) derivatives

Answer 5

Sulphasalazin, mesalazine

Olsalazine balsalazide

Question 6

1st generation retinoids

Answer 6

tretinoin
isotretinoin
alitretinoin

Question 7

2nd generation retinoids

Answer 7

acitretin

Question 8

3rd generation

Answer 8

bexarotene
adaplene
tazarotene

Question 9

Antibodies against T cells

Answer 9

Muromonab-CD3
Basiliximab
Daclizumab

Question 10

Antibodies against B cells

Answer 10

Rituximab
ocrelizumab
Alemtuzumab

Question 11

Antibodies against TNFalpha

Answer 11

Adalimumab
Certolizumab pegol
etanercept
golimumab
infliximab

Question 12

IL-1 receptor antagonist

Answer 12

Anakinra

Question 13

Anti IL1 beta

Answer 13

canakinumab

rilonacept

Question 14

anti IL-5

Answer 14

reslizumab

Question 15

anti IL-6

Answer 15

tocilizumab

sarilumab

Question 16

anti IL-17

Answer 16

secukinumab
ixekizumab
brodalumab

Question 17

anti IL-12/23

Answer 17

ustekinumab

Question 18

anti IL-23

Answer 18

Guselkumab

Question 19

Anti B lymphocyte stimulator protein

Answer 19

Belimumab

Question 20

antibodies for integrin

Answer 20

natalizumab

vedolizumab

Question 21

antibody against complement factor 5

Answer 21

eculizumab

Question 22

antibody against FCe part of IgE

Answer 22

omalizumab

Question 23

CTLA4-containing fusion protein

Answer 23

abatacept