Immunology and Serology Flashcards
the study of all the aspects
of the immune system
immunology
a division of immunology that
specializes in the laboratory detection &
measurement of antigens & antibodies
serology
Specific production of antigen;
no false positives
specificity
The binding of antigen to a specific
antibody plays an important role in the
diagnosis of diseases using the different
tests
the principle of immunology and serologic methods
The action of an antibody when it
cross-links multiple antigens producing
clumps of antigens
agglutination
it is a stage of agglutination that represents the physical attachment
of antibody molecules to antigens and becomes sensitive
sensitization
stage of agglutination that establish of cross-links between
sensitized particles & antibodies, resulting in aggregation and visible to the naked eye, also clumping
lattice formation
what are the type of agglutination reactions and their examples?
direct agglutination - blood typing
passive/indirect - rheumatoid factor latex test
reverse passive - c-creative protein test
Competition between particulate &
soluble antigens for limited
antibody-combining sites.
agglutination inhibition
lack of agglutination mean positive
agglutination inhibition
Branch of immunology which deals with
the uses of immunologic principles to
study & identify the different blood groups
immunohematology/blood banking
who discovered the ABO blood group?
karl landsteiner
in what year did the ABO blood group discovered?
1900
who discovered the blood type AB?
Alfred von De Castello & Adriano Sturli
direct or forward typing
cell typing
