Immunology and Serology

Question 1

What is an antibody?

Answer 1

protein produced by a plasma cell in the lymphatic system or bone marrow

Question 2

What is serology?

Answer 2

study of serum reactions between an antigen and its antibody

Question 3

Innate immune system aka

Answer 3

passive immunity

Question 4

Adaptive immunity includes _______________.

Answer 4

a “memory” that makes future responses against specific antigen more effective

Question 5

The Innate immune system does not possess ________.

Answer 5

a “memory”

Question 6

Acquired immune system aka

Answer 6

active immunity

Question 7

What does the Humoral part consist of?

Answer 7

B cells

Question 8

What does the Cell Mediated part consist of?

Answer 8

T cells

Question 9

How are antibodies produced?

Answer 9

B cells are stimulated by antigens

Question 10

What are the 5 majors classes of antibody proteins called?

Answer 10

immunoglobulins

Question 11

What are antibody proteins produced by?

Answer 11

produced by plasma cell

Question 12

What is measured to diagnose failure of passive immunity?

Answer 12

IgG

Question 13

What antibody protein can cross the placenta?

Answer 13

IgG

Question 14

Which antibody protein is the most abundant?

Answer 14

IgG

Question 15

Which antibody protein is the first to be activated in an initial attack of antigen?

Answer 15

IgM

Question 16

IgM is the ____________________.

Answer 16

primary immune response

Question 17

Where is IgA found?

Answer 17

on mucous membranes and in colostrum

Question 18

What is IgA stimulated by?

Answer 18

IN vax

Question 19

What does IgD do?

Answer 19

activates and suppresses lymphocyte activity

Question 20

Where is IgD found?

Answer 20

in large quantities in cell membrane of lymphocytes

Question 21

What is the function of IgD?

Answer 21

unknown function

Question 22

What is IgE?

Answer 22

mediator in allergic responses and parasitic infection

Question 23

Helper T cells have no ___________.

Answer 23

no cytotoxic or phagocytic activity

Question 24

What are the 3 types of T cells?

Answer 24

Killer (cytotoxic) T cells, Helper T cells, Suppressor T cells

Question 25

What causes the Suppressor T cell population to increase?

Answer 25

allergy shots

Question 26

In puppies and kittens, where does a majority of immunoglobulins come from?

Answer 26

95% of circulation immunoglobulins come from the absorption of colostrum shortly after birth

Question 27

Phagocyte deficiencies respond poorly to ______.

Answer 27

antibiotics

Question 28

What is the #1 cause of death in dogs?

Answer 28

tumors

Question 29

What is one of the prevalent tumors in dogs and cats?

Answer 29

lymphomas

Question 30

What is sensitivity?

Answer 30

proportion of positives that are correctly identified

Question 31

What is specificity?

Answer 31

proportion of negatives that are correctly identified

Question 32

What is the advantage of ELISA microwells?

Answer 32

you can batch samples (run one test on multiple patients)

Question 33

What does a RIM do?

Answer 33

use signal generating component “colloidal gold”

Question 34

What is an example of a RIM test?

Answer 34

Witness HW test

Question 35

What is tuberculosis caused by?

Answer 35

mycobacterium bovis (m. bovis)

Question 36

What are the 3 type of tuberculosis?

Answer 36

human, avian, bovine