Immunology Flashcards
fluctuating muscle weakness worse with exercise, ptosis, autoantibodies against Ach
myasthenia gravis
workup for myasthenia gravis
edrophonium (Tensilon) test: inhibits Acetylcholinesterase, increasing Ach and reversing ptosis.
CT/MRI to look for thymomoa
EMG: deccreased response
tx myesthenia gravis
acetylcholinesterase inhibitors (doneprezil, rivastigmine)
immunosuppressive meds
thymectomy
necrotizing medium vessel vasculitis
weight loss
neuropathy
polyarteritis nodosa
symmetrical, proximal muscle weakness
racoon eyes
Gottron’s patches (purpule patches over knuckles)
polymyositis
dermatomyositis
initial GU or GI infection
noninfectious urethritis, arthritis, conjunctivitis
Reactive Arthritis
tx for reactive arthritis
none
antibiotics for infections
coticosteroids and TNF alfpha for inflammation
sulfasalazine (anti-inflammatory) for chronic cases
*usually self-limited course in 3-12 months
morning stiffness
symmetric joint involvement
Boutonniere defomity
positive RF
rheumatoid arthritis
what antibiotics are CI in pregnancy
Doxy
TMP/Sulpha
rifampin
TB tx
dose of Epi for anaphylaxis
IM 1:1000 .3-.5mg
position for anaphylactic reaction
trendelenburg position
complication of SLE
osteoporosis
pharamceutical for SLE
hydroxychloroquine
test for Mono
heterophile ab titer