Immunology

Question 1

fluctuating muscle weakness worse with exercise, ptosis, autoantibodies against Ach

Answer 1

myasthenia gravis

Question 2

workup for myasthenia gravis

Answer 2

edrophonium (Tensilon) test: inhibits Acetylcholinesterase, increasing Ach and reversing ptosis.
CT/MRI to look for thymomoa
EMG: deccreased response

Question 3

tx myesthenia gravis

Answer 3

acetylcholinesterase inhibitors (doneprezil, rivastigmine)
immunosuppressive meds
thymectomy

Question 4

necrotizing medium vessel vasculitis
weight loss
neuropathy

Answer 4

polyarteritis nodosa

Question 5

symmetrical, proximal muscle weakness
racoon eyes
Gottron’s patches (purpule patches over knuckles)

Answer 5

polymyositis

dermatomyositis

Question 6

initial GU or GI infection

noninfectious urethritis, arthritis, conjunctivitis

Answer 6

Reactive Arthritis

Question 7

tx for reactive arthritis

Answer 7

none
antibiotics for infections
coticosteroids and TNF alfpha for inflammation
sulfasalazine (anti-inflammatory) for chronic cases
*usually self-limited course in 3-12 months

Question 8

morning stiffness
symmetric joint involvement
Boutonniere defomity
positive RF

Answer 8

rheumatoid arthritis

Question 9

what antibiotics are CI in pregnancy

Answer 9

Doxy

TMP/Sulpha

Question 10

rifampin

Answer 10

TB tx

Question 11

dose of Epi for anaphylaxis

Answer 11

IM 1:1000 .3-.5mg

Question 12

position for anaphylactic reaction

Answer 12

trendelenburg position

Question 13

complication of SLE

Answer 13

osteoporosis

Question 14

pharamceutical for SLE

Answer 14

hydroxychloroquine

Question 15

test for Mono

Answer 15

heterophile ab titer

Question 16

tx for allergic rhinitis

Answer 16

oxymetazoline: adrenergic agonist, vasoconstriciton of nasal mucosa

Question 17

HIV supportive botanicals

Answer 17

hypericum, glycerhiza, echinacea

Question 18

what drug inhibits complement dependent ag ab reaction

Answer 18

hydrochychloroquine

can be used in SLE or RA

Question 19

what dose of epi is indicated for child with anaphylaxis

Answer 19

.01mg/kg 1:1000 IM

Question 20

tx for fibromyalgia

Answer 20

cyclobenzaprine: muscle relaxant

Question 21

5HTP is not safe with what pharamceutical

Answer 21

fluoxetine due to serotonin syndrome

Question 22

yergosens test

Answer 22

bicipital tendonitis

Question 23

test for sacroilitis

Answer 23

Yeomans

Question 24

effects asymetrical, larger joints with osteophyte involvement

Answer 24

osteoarthritis

Question 25

Heberdenes nodes seen in

Answer 25

osteoarthritis

Question 26

botanicals for osteoarthritis

Answer 26

harpagophytum
smilax
curcuma
boswelia

Question 27

workup for guillan barret

Answer 27

CSF analysis

Question 28

schirmers test

Answer 28

for eye involvement in sjogrens syndrome

Question 29

complication of guillan barret

Answer 29

interstitial lung disease