IMMUNOLOGY Flashcards
what is the definition of autoimmunity
reaction to host tissue resulting in chronic inflammation
what is the definition of hypersensitivity
overreaction to an antigen
what cell is there an abundance of in healthy skin
T cells
what happens when keratinocytes are activated by sunlight/pathogens
immune response
what does keratin produce in its immune response to sunlight/pathogens
AMPs
cytokine
chemokines
which immune cell is found it the prickle cell layer
Langerhans cells
what type of immune cell are Langerhans cells
dendritic cell
which cells do Langerhans cells activate
CD8+ T cells
what immune cells are found in the dermis
dendrites
macrophages
CD4+ and CD8+ T cells
NK cells
fibroblasts
neutrophils
mast cells
which type of T helper cell causes psoriasis
TH1
which type of T helper cell causes atopic dermatitis
TH2
which type of T helper cell causes atopic dermatitis and psoriasis
TH17
which immune cell is involved in both psoriasis and atopic dermatitis
CD4+ T helper cells
how does excessive sunlight affect your skins immune system
causes immunosuppression
