Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

J Derm > Dermatitis > Flashcards

Dermatitis Flashcards

You may prefer our related Brainscape-certified flashcards:
Dermatology Board Prep flashcards
1
Q

aetiology of contact allergic dermatitis

A

in response to chemicals, perfume, nickel, latex, plants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

presentation of contact allergic dermatitis (location, worse areas)

A

location - around the site of irritation

worse at thin skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the immunological response in contact allergic dermatitis (5 steps and hypersensitivity type)

A

type IV hypersensitivity - delayed response

  1. Langerhans process antigen
  2. antigen passed on to T helper cells in dermis
  3. T helper cells take antigen to lymphatics
  4. antigen presented to other cells
  5. when antigen is encountered again = recognised = T cells proliferate and migrate to skin = dermatitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what investigation would you do if you suspected contact allergic dermatitis

A

patch test

blood IgE

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the difference between contact irritant dermatitis and contact allergic dermatitis

A

contact irritant dermatitis doesnt involve IgE (NOT an allergic response)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

aetiology of contact irritant dermatitis

A

soap, detergents, cleaning products (eg under jewellery)

urine = nappy rash
lick lip dermatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

aetiology of atopic eczema/atopic dermatitis

A

genetic (filaggrin mutation = filament aggregating protein)

environmental factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what other conditions are associated with atopic eczema

A

asthma, rhinitis, food allergy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what age does eczema typical present

A

school aged children

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what does atopic eczema look like on histology

A

spongiosis (white spaces in cells = looks like a sponge) and inflammatory infiltrate

NOTE - all other dermatitis have spongiosis on histology, but no inflammatory infiltrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

first line treatment of atopic eczema

A

emollients (eg e45) to soothe and hydrate

avoid irritants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

second line treatment of atopic eczema (after emollients)

A

topical steroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

third line treatment of atopic eczema (after emollients and topical steroids)

A

treat infection
phototherapy
immunosuppressants

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

how does chronic eczema present

A

excoriations (scratch marks)
lichenification - thickening of skin bc of scratching
may be infected

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how does staph aureus infected chronic eczema present

A

yellow crusting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

aetiology discoid eczema

A

scratching of dry skin and irritation of skin

17
Q

how does discoid eczema present

A

red plaques in well defined discs (DISCoid eczema)

can appear anywhere, unusual on face/scalp

18
Q

what is pompholyx eczema associated with

A

oedema

19
Q

how does photoinduced dermatitis present

A

stops at collar level

20
Q

aetiology of lichen simplex dermatitis

A

scratch = itch cycle

21
Q

location of lichen simplex dermatitis

A

back of neck, side of legs

22
Q

aetiology of stasis dermatitis

A

hydrostatic pressure (eg oedema) = skin under pressure

23
Q

what can stasis dermatitis predispose

A

venous leg ulcer

24
Q

how do all dermatitis present on histology

A

spongiosis (white spaces in between cells = look slike a sponge)

25
Q

what 2 infections are associated with dermatitis

A

herpes simplex virus infection

staph aureus infection

26
Q

how does herpes simplex virus associated with dermatitis present

A

monomorphic punched out lesions

27
Q

what does herpes simplex virus infection associated with dermatitis cause

A

eczema herpeticum

28
Q

how does staph aureus infection associated with dermatitis present

A

yellow crusting

29
Q

how does staph aureus manage to infect someone with dermatitis

A

scratching of skin = skin becomes broken

30
Q

how is staph aureus infected dermatitis treated

A

PO flucloxacillin

31
Q

hypersensitivity of contact allergic dermatitis

A

type IV hypersensitivity - delayed response

32
Q

which cells process the antigen in contact allergic dermatitis

A

Langerhans

33
Q

what is the role of T cells in contact allergic dermatitis

A

Langerhans pass on antigen to T helper cell

T helper cell takes antigen to lymphatics

34
Q

why does the lymphatics take the antigen in contact allergic dermatitis

A

to present it to other cells

whenever any of them come in contact with it again = dermatitis occurs

35
Q

which condition is filagrin associated with

A

atopic dermatitis/eczema

36
Q

what is filagrin

A

filament aggregating protein

37
Q

why doesnt everyone with filagrin get eczema

A

need skin barrier to be impaired

J Derm (23 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions