Immune system Flashcards

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1
Q

what is innate immunity

A

the body’s initial generalized defenses against pathogens

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2
Q

what is the most common granulocyte

A

neutrophils

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3
Q

what do neutrophils do

A

attract additional white blood cells to sit of tissue damage, phagocytose bacteria

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4
Q

what do eosinophils do

A

responsible for allergic and asthmatic responses, indicated infection by parasite,

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5
Q

what do basophils do

A

involved in allergic responses and parasite infections, and are often responsible for the release of histamine

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6
Q

what does histamine do

A

stimulates blood vessel dilation

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7
Q

what are monocytes

A

large, long lived immune cells that can differentiate into macrophages and dendritic cells

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8
Q

what is the role of macrophages

A

to phagocytize dead cells and pathogens

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9
Q

what cells are involved in innate immunity

A

macrophages, natural killer cells, basophils, eosinophils, neutrophils

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10
Q

what cells are involved in adaptive immunity

A

B cells and T cells

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11
Q

what cells are involved in both innate and adaptive immunity

A

dendritic cell and natural killer T-cell

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12
Q

what are the two types of adaptive immunity

A

cell-mediated and humoral

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13
Q

what cell mediates cell-mediated immunity

A

T lymphocytes

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14
Q

what mediates humoral immunity

A

B lymphocytes

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15
Q

where do T lymphocytes develop and mature

A

develop in the bone marrow and mature in the thymus

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16
Q

what are the two types of histocompatability proteins

A

MHC I and MHC II

17
Q

what histocompatability protein do cytotoxic T cells respond to

A

antigens presented by MHC I complexes

18
Q

what histocompatability protein do T helper cells respond to

A

antigens presented by MHC II complexes

19
Q

what histocompatability protein do natural killer T cells respond to

A

they respond to antigens presented by other types of cells

20
Q

what is the function of memory T cells

A

allow for a quicker more targeted response if the antigen reappears

21
Q

what do regulatory or suppressor T cells do

A

tone down the T cell response to self cells or following an infection

22
Q

where do B lymphocytes develop and mature

A

they develop and mature in bone marrow

23
Q

what is the function of B cells

A

they create and express antibodies that have a high affinity for antigens

24
Q

explain the structure of immunoglobulins

A

they consist of two chains, a light chain and a heavy chain, which are held together with disulfide bonds

25
Q

what can active immunity be caused by

A

exposure to a pathogen or a vaccination

26
Q

what is passive immunity caused by

A

the transfer of antibodies from one individual to another

27
Q

what do lymph nodes and the spleen do

A

they are reservoirs for white blood cells and filters for lymph, remove antigen presenting cells and foreign matter and activate the immune system when necessary