Immune system Flashcards

1
Q

What happens when in case of a laceration with bacteria or virus entering through

A

Cut will encounter specific kinds of white blood cells that ingest pathogens by phagocytosis. One type being a macrophage. After consuming ht e pathogen, the macrophage is able to put parts of the ingested antigens on its cell membrane to alert patrolling Cells. The macrophage then takes o the role of Antigen presenting cell.

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2
Q

What cells function as antigen presenting cells

A

*Macrophages after consuming a pathogen
*Dendritic cells
*B cells

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3
Q

Macrophages

A

*consume pathogens and display them becoming antigen presenting cells
*produce cell signaling molecules, cytokines

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4
Q

Cytokines function

A

broadcast the location of pathogens to other white blood cells

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5
Q

histamine function

A

triggers capillary permeability and vasodilation.
These effects make it easier for more white blood cells to leak from the capillaries into the area in need of defense.

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6
Q

Interferons

A

Prevent virus replication

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7
Q

External innate immune system

A

*skin
*hair
*mucus
*earwax
*secretions (acid, salt, enzymes)
*Nomrla flora

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8
Q

Internal innate immune system

A

*antimicrobials
*inflammation
*interferons
*complement
*phagocytes (including APC)

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9
Q

Adaptive immune system Cytotoxic T cells

A

kill pathogens

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10
Q

B cells

A

Adaptive immune system and produce antibodies

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11
Q

helper T cells activated by

A

APC

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12
Q

T cells undergo maturation in

A

the thymus and mature T cells become activated into helper T cells, cytotoxic T cells, and memory cells

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13
Q

Helper T cells secrete

A

interleukins

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14
Q

interleukins

A

Chemical messengers that trigger the action of other cells
Ex. The attack of forge in cells by cytotoxic T cell

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15
Q

Cell mediated immunity (humoral immunity)

A

a type of adaptive immunity in which T lymphocytes attack parasitic worms, cancer cells, transplanted tissue, or cells that contain pathogens.

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16
Q

cytotoxic T cells

A

are specialized to kill infected or abnormal cells. some produce memory t cells that respond to subsequent infections

17
Q

helper T cells

A

secrete cytokines that stimulate the division of T and B cels while alerting other types of WBCs

18
Q

regulatory (suppressor) T cells

A

inhibit T and B cells to stop the immune response

19
Q

B cells involved in

A

humoral-mediated immunity. They encounter freely circulating antigens

20
Q

plasma cells

A

secrete antibodies that bind to antigens

21
Q

memory cells produce

A

antibodies but only during a subsequent infection

22
Q

neutrophiles

A

account for most of the white blood cells in the blood stream. phagocytes that are usually the first to arrive at the site of infection

23
Q

eosinophils

A

regulate inflammatory responses and release chemicals that kill foreign invaders, often parasitic worms

24
Q

mast cells and basophils

A

both release histamine to promote inflammation and heparin to inhibit clotting

25
Q

macrophages

A

largest leukocytes that engulf debris and pathogenic microorganisms

26
Q

dendritic cells

A

activate T cells

27
Q

natural killer cells

A

not phagocytes; they destroy cells that have been infected with a pathogen by binding to them and releasing granzymes that trigger apoptosis

28
Q
A