ILD Flashcards

1
Q

What is interstitium

A

-it’s the area between the capillary endothelium and alveolar epithelium

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2
Q

What are the types of interstitium

A

-axial
-peripheral
-centrilobular

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3
Q

What is axial interstitium

A

-it’s the interstitium that covers the bronchus to respiratory bronchiole

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4
Q

What is peripheral interstitium

A

-it’s the interstitium that covers the pulmonary veins, lymphatics and septae

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5
Q

What is cetrilobular interstitium

A

-it’s an interstitium that covers from capillary endothelium to the alveolar epithelium

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6
Q

What are the types of ILD

A

-known
-unknown
-granuloma

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7
Q

What are the known ILD

A

-drugs (Bleomycin, Amiodarone)
-exposure (Pneumonoconiosis and HP)

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8
Q

What is the unknown ILD

A

-Idiopathic Pulmonary Fibrosis

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9
Q

What is the granuloma ILD

A

-sarcoidosis

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10
Q

What is the risk age of IPF

A

-middle age (40-70)

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11
Q

What are symptoms of IPF

A

-dry cough
-SOB

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12
Q

What are the signs of ILP

A

-Velcro crackles
-digital clubbing

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13
Q

What is the X-ray finding of ILP

A

ABBBB
-asymetrical
-abnormal >90%
-bilateral
-basal
-peripheral

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14
Q

What is the X-ray pattern of ILP

A

-reticular
-reticulonodular

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15
Q

What is the CT finding of early ILP

A

-patchy, peripheral, reticular subpleural and basal
-ground glass

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16
Q

What is the CT finding of late ILP

A

-honey comb appearance

17
Q

What is the function of BAL and TBB in ILP

A

-to rule out alternate diagnoses

18
Q

What are the major criteria of ILP

A

-exclusion of known ILD
-abnormal lung function
-hypoxia
-CT: bibasal reticular
-BAL and TBB shows no alternate diagnoses

19
Q

What are the minor criteria of ILP

A

-age>50
-dyspnea
-ilness>3 months

20
Q

What are the ttt for ILP

A

-steroids
-cytotoxic drugs (azathioprim, cyclophosphamide)
-anti-fibrotic (calchicine, prifenidone)

21
Q

What are the indications of good prognosis in ILP

A

-age<50
-female
-symptoms<1 year
-CT; ground glass

22
Q

What is the contraindication of lung transplantation

A

-age>60
-mental unstable
-extrapulmonary disorder