Fungal Disease of Lung

Question 1

What is the most organ affected by the fungal infection

Answer 1

-lung
-skins

Question 2

What is the risk factor of histoplasmosis

Answer 2

-farmer exposed to the bats and birds excreta

Question 3

What is the risk factor of spirotrichosis

Answer 3

-farmer with wound exposed to soil

Question 4

What is the main risk factors of fungal infection

Answer 4

Immunosupression
-genetic
-congenital
-acquired
-postspenectomy
-bone marrow transplantation

Question 5

What is the yeast causative agent

Answer 5

candidiasis

Question 6

What is the hypae causative agent

Answer 6

aspargellosis

Question 7

What is the dimorphic fungal causative agent

Answer 7

-histoplasmosis
-blancomycosis
-coccidiomycosis

Question 8

What is PJP

Answer 8

-unicellular fungus
-the most common opportunistic infection in patient HIV patient

Question 9

What is the symptoms of PJP

Answer 9

-fever
-nonproductive cough
-progressive exertion dyspnea

Question 10

What is the stain used in PJP

Answer 10

GMS stain

Question 11

What is the microscopic findings of the PJP

Answer 11

-amphopheric
-foamy plugs of parasites
-cellular debris

Question 12

What is the immunofluorescene findings of PJP

Answer 12

-headshape
-cupshape
-crescent

Question 13

What is the best investigation in PJP

Answer 13

-sputum induction
-the least invasive and quickest

Question 14

What is the ttt of PJP

Answer 14

-TMP-SMX (first line)
-dapsone

Question 15

What is the major predisposing factors leading to aspargellosis

Answer 15

-neutropenia
-corticosteroid

Question 16

What does the spore of aspergillus causes

Answer 16

-ABPA

Question 17

What are the types of aspargellosis

Answer 17

-invasive
-chronic (aspargelloma)
-allergic (ABPA)

Question 18

What are the symptoms of invasive aspergillosis

Answer 18

-hemoptysis
-fever
-leukocytosis (viral infection)

Question 19

What is the radiological findings of aspargellosis

Answer 19

-halo signs

Question 20

What is the radiological findings of aspargelloma

Answer 20

-radiolucent crescent

Question 21

What is the type of cell of Histoplasma capsulatum

Answer 21

-intracellular pathogens
-hides inside the macrophage

Question 22

What is the general finding of histoplasmosis

Answer 22

-upper love cavitation
-caseating necrosis

Question 23

What is the post-ttt finding of histoplasmosis

Answer 23

-calcification and fibrosis giving treebark appearance

Question 24

What is the microscopic finding of histoplasmosis

Answer 24

-thin halo (due to its character that hides inside of the macrophage)

Question 25

What is the dissemination finding of histoplasmosis in case of immunosupressed patients

Answer 25

-focal accumulation of mononucleated phagocytes

Question 26

What is the clinical presentation of histoplasmosis

Answer 26

-TB like symptoms

Question 27

What is blastomycosis

Answer 27

-soil inhabited -dimorphic fungus

Question 28

What are the clinical forms of blastomycosis

Answer 28

-pulmonary -dissemination -primary cutaneous

Question 29

What are the symptoms of pulmonary blastomycosis

Answer 29

-acute productive cough -chest pain -headache -night sweat -loss weight

Question 30

What are the general finding of blastomycosis

Answer 30

-suppurative granuloma

Question 31

What are the microscopic of blastomycosis

Answer 31

-double contoured cell wall -visible nuclei

Question 32

What is the characters of coccidioides based on; -hypersensitivity -symptoms -lesion morphology

Answer 32

-delayed type -typically asymptomatic -as histoplasmosis

Question 33

When will the pyogenic reaction superimposed in coccidiomycosis

Answer 33

-the rupture of spherules releasing endospores

Question 34

When will the pyogenic reaction superimposed in coccidiomycosis

Answer 34

-the rupture of spherules releasing endospores