Hypoglycemie Flashcards

0
Q

Physiopathologie hypoglycémie

A

Gly<9,5g/L (2,8 mmol/L) ou 0,6 si diabétique (3,3mmol/L)

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1
Q

Triade de Whipple

A

Signes neuroglucopenie + gly↘️ + correction symptômes après resucrage

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2
Q

Signes neuroglucopenie

A

Tb attention, tb mnésique, désorientation, état pseudo ébriété, paresthésie, anxiété, excitation, irritabilité, dépression, agressivité, diplopie, hallucinations olfactives ou visuelles, vertiges, céphalées

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3
Q

Étiologies hypoglycémie diabétique

A

Surdosage insuline ou sulfamide, OH, erreur diététique, gastroparesie, activité sportive, IRn, IH, IS…

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4
Q

Étiologie hypoglycémie non diabétique

A

OH, Iatro, toxique, IS
Déficit hormone contre régulation (Glucagon, cortisone adrénaline, ACTH) déf GH, IAH
Insulinome
Tumeurs sécrétantes de IGF2
Acidose lactique, accès palustre
Sécrétion Ac antiinsuline, hypersécrétion non tumorale d’insuline

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5
Q

Paraclinique hypoglycémie

A

Créat, TP, cortisol a 8h

+/- épreuve de jeune (72h ou stop si clinique ou gly<0,3g/L)

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6
Q

Pec hypoglycémie

A

URGENCE resucrage 15g PO
2-3 ampoule G30 IV
Glucagon 1mg IM ou SC +/- vvp et G10 1L/4h et 1L/12h
Ou perf glc (si IH ou sulfamide)

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7
Q

Épreuve de jeune : gly↘️↘️ insuline ↗️ peptide C ↗️

A

Sulfamide ou insulinome

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8
Q

Épreuve de jeune : gly↘️↘️ insuline ↗️ peptide C ↘️

A

Prise insuline

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9
Q

Épreuve de jeune : gly↘️↘️ insuline ↘️ peptide C ↘️

A

Tumeur IGF2

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10
Q

Insulinome clinique

A

Hypoglycémie et prise de poids

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11
Q

Insulinome paraclinique

A

Gly3MUI/L et peptide C>0,6ng/L

Scanner pancréas + écho endoscopie + octreoscann

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