Hypertension Flashcards

1
Q

Pathological hallmark of accelerated phase (malignant) hypertension?

A

Fibrinoid necrosis

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2
Q

Causes of secondary hypertension?

A
Renal disease
Endocrine disease 
Pregnancy
Aortic disease 
Renal artery stenosis 
Drug therapy
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3
Q

Symptoms of malignant hypertension

A

Headache/ cerebral haemorrhage
Visual disturbance
Acute renal failure
Acute heart failure

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4
Q

What does the assign score estimate?

A

Risk of having a cardiovascular event in the next 10 years

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5
Q

What percentage of the population are hypertensive?

A

25%

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6
Q

What in Conn’s syndrome an excess of?

A

Aldosterone

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7
Q

What is Cushing’s syndrome an excess of?

A

Corticosteroid

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8
Q

What is phaeochromocytoma an excess of?

A

Noradrenaline

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9
Q

What can benign hypertension lead to?

A
Left ventricular hypertrophy 
Congestive cardiac failure 
Increases atheroma 
Increases aneurysm rupture 
Renal disease
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10
Q

Define stage 1 hypertension

A

Clinic BP > 140/90

ABPM/HBPM > 135/85

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11
Q

Define stage 2 hypertension

A

Clinic BP > 160/100

ABPM/HBPM > 150/95

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12
Q

Define severe hypertension

A

Clinic BP > 180/110

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13
Q

Investigations for all hypertensive patients

A

Urine - presence of protein
FBC - glucose, creatinine, glomerular filtration rate, cholesterol
U+E’s
Examine funds for hypertensive retinopathy
12-lead ECG

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14
Q

Step 1 hypertension treatment if aged 55 or less

A

ACE inhibitor or ARB

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15
Q

Step 1 hypertension treatment if over 55 or black

A

Calcium-channel blocker

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16
Q

Step 1 hypertension treatment if pregnant

A

Beta blocker

17
Q

Step 2 hypertension treatment for everyone

A

ACE inhibitor (or ARB) + Calcium-channel blocker

18
Q

Step 3 hypertensive treatment for everyone

A

ACE inhibitor (or ARB) + Calcium-channel blocker + thiazide-like diuretic

19
Q

Treatment for patient with hypertension and heart failure

A

Spironolactone

20
Q

Treatment of malignant hypertension

A

Low dose spironolactone (monitor U+E’s)