Hypersensitivity Flashcards

1
Q

What are the defects in lymphocyte activation and function?

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2
Q

What’s the defect of X-linked SCID?

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3
Q

What’s the defect of autosomal recessive SCID due to ADA, PNP deficiency?

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4
Q

Describe the Autosomal recessive SCID due to other causes

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5
Q

Describe the X-linked agammaglobulinemia

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6
Q

Describe Ig heavy chain deficiencies

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7
Q

Explain DiGeorge Syndrome

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8
Q

What is hypersensitivity?

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9
Q

Contrast immediate and delayed-hypersensitivity

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10
Q

What are the classifications of hypersensitivity?

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11
Q

What is common to all hypersensitivities?

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12
Q

Discuss type I hypersensitivity

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13
Q

What common allergens cause type 1 hypersensitivity?

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14
Q

How do allergens interact with Helper T cells, and B cells?

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15
Q

What are the Mast Cell Degranulation mediators?

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16
Q

What are the primary effects of histamine, heparin?

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17
Q

What are the etiology of Allergies?

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18
Q

Give the examples of types of type 1 hypersensitivity

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19
Q

What are the clinical methods to detect Type 1 hypersensitivity?

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20
Q

What is Anaphylaxis?

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21
Q

What is Bronchial Asthma?

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22
Q

What is Various allergic diseases?

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23
Q

Outline the Desensitization: the blocking antibody theory

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24
Q

What is the type II hypersensitivity?

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25
Q

What are the cytotoxic examples of type II hypersensitivity ?

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26
Q

What’s the significance of Rhogam?

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27
Q

Describe Type II hypersensitivity (non-cytotoxic)

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28
Q

What are the diseases of Type II hypersensitivity?

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29
Q

What is a type 3 hypersensitivity?

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30
Q

What’s the effect of type 3 hypersensitivity ?

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30
Q

What’s the effect of type 3 hypersensitivity ?

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31
Q

Describe Generalized type III hypersensitivity

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32
Q

What is Systemic Lupus erythematous?

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33
Q

What is Polyarteritis nodosa?

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34
Q

What is Poststreptococcal glomerulonephritis?

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35
Q

What is serum sickness?

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36
Q

What is Arthurs reaction?

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37
Q

What is the type IV Hypersensitivity?

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38
Q

What cause type IV hypersensitivity?

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39
Q

What are the steps of Type IV sensitivity ?

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40
Q

What is the effect of prolonged DTH?

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41
Q

What intracellular pathogens and contact antigens produce a delayed Type IV hypersensitivity?

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42
Q

What type of hypersensitivity is caused by Rheumatoid arthritis?

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43
Q

2hat are the key elements of each hypersensitivity type?

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