Hypersensitivity Flashcards

1
Q

What are the defects in lymphocyte activation and function?

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2
Q

What’s the defect of X-linked SCID?

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3
Q

What’s the defect of autosomal recessive SCID due to ADA, PNP deficiency?

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4
Q

Describe the Autosomal recessive SCID due to other causes

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5
Q

Describe the X-linked agammaglobulinemia

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6
Q

Describe Ig heavy chain deficiencies

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7
Q

Explain DiGeorge Syndrome

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8
Q

What is hypersensitivity?

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9
Q

Contrast immediate and delayed-hypersensitivity

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10
Q

What are the classifications of hypersensitivity?

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11
Q

What is common to all hypersensitivities?

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12
Q

Discuss type I hypersensitivity

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13
Q

What common allergens cause type 1 hypersensitivity?

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14
Q

How do allergens interact with Helper T cells, and B cells?

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15
Q

What are the Mast Cell Degranulation mediators?

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16
Q

What are the primary effects of histamine, heparin?

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17
Q

What are the etiology of Allergies?

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18
Q

Give the examples of types of type 1 hypersensitivity

19
Q

What are the clinical methods to detect Type 1 hypersensitivity?

20
Q

What is Anaphylaxis?

21
Q

What is Bronchial Asthma?

22
Q

What is Various allergic diseases?

23
Q

Outline the Desensitization: the blocking antibody theory

24
Q

What is the type II hypersensitivity?

25
Q

What are the cytotoxic examples of type II hypersensitivity ?

26
Q

What’s the significance of Rhogam?

27
Q

Describe Type II hypersensitivity (non-cytotoxic)

28
Q

What are the diseases of Type II hypersensitivity?

29
Q

What is a type 3 hypersensitivity?

30
Q

What’s the effect of type 3 hypersensitivity ?

30
Q

What’s the effect of type 3 hypersensitivity ?

31
Q

Describe Generalized type III hypersensitivity

32
Q

What is Systemic Lupus erythematous?

33
Q

What is Polyarteritis nodosa?

34
Q

What is Poststreptococcal glomerulonephritis?

35
Q

What is serum sickness?

36
Q

What is Arthurs reaction?

37
Q

What is the type IV Hypersensitivity?

38
Q

What cause type IV hypersensitivity?

39
Q

What are the steps of Type IV sensitivity ?

40
Q

What is the effect of prolonged DTH?

41
Q

What intracellular pathogens and contact antigens produce a delayed Type IV hypersensitivity?

42
Q

What type of hypersensitivity is caused by Rheumatoid arthritis?

43
Q

2hat are the key elements of each hypersensitivity type?