Autoimmunity And Transplantation Flashcards by Jhaunte Braithwaite | Brainscape

Q

What’s the significance of immunological tolerance?

A

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Q

Contrast central and peripheral tolerance

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Q

Contrast central tolerance of T cells

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Q

Contrast positive and negative selection

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Q

How are self-antigens expressed in the thymus?

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Q

What is autoimmune polyglandular syndrome?

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Q

What are tolerogens?

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Q

What happens when tolerance fails?,

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Q

What are the causes of autoimmunity?

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Q

What causes MHC locus disease?

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Q

What are immune privileged sites?

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Q

What are the significance of CTLA-4 for autoimmunity?

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Q

Which immune reactions can lead to autoimmunity?

A

Type 2,3, and 4

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Q

What is type 2 cytotoxicity?

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Q

What are the non-cytotoxic type 2 types of autoimmunity?

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Q

How is pernicious anemia a type 2 non-cytotoxic aytiimmunity?

A

Q

How are antibodies involved in type 2 autoimmune/hypersensitivity?

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Q

What is good pastures?

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Q

What hypersensitivity type are systemic autoimmune diseases?

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Q

What is lupus?

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Q

What is the use of antinuclear antibody screening

A

Q

What is rheumatoid arthritis?b

A

Q

What are assoc8ated with rheumatoid association?

A

Q

Describe type 4 autoimmune diseases

A

Q

What is Hashimoto’s thyroiditis?

A

Q

What type of hypersensitivity leads to type 2 diabetes

A

Q

What is the impact of T cells?

A

Q

What are the common types of hypersensitivity?

A

Q

Summarize this deck

A