Humoral Immune Response II

Question 1

Contrast intracellular and extracellular terminology

Answer 1

Question 2

Define cell mediated immunity and humoral mediated immunity

Answer 2

Question 3

Summarize effector function of antibodies

Answer 3

Question 4

What’s the role of Fab in neutralization ?

Answer 4

Question 5

What’s the role of opsonization of Fab and Fc?

Answer 5

Question 6

Give the characteristics of FcyRI

Answer 6

Question 7

Give the characteristics of FcyRIIA

Answer 7

Question 8

Give the characteristics of FcyRIIB

Answer 8

Question 9

Give the characteristics of FcRIIIA

Answer 9

Question 10

Give the characteristics of FceRI

Answer 10

Question 11

What is the significance of ADCP?

Answer 11

Question 12

What do NK cells do?

Answer 12

Question 13

What do eosinophils do?

Answer 13

Question 14

What are the complement-dependent cytotoxicity ?

Answer 14

Question 15

What is the IgG function?

Answer 15

Question 16

What is IgM?

Answer 16

Question 17

Whaat is IgA?

Answer 17

Question 18

What is IgE?

Answer 18

Question 19

What are the functions of antibodies at special anatomical sites?

Answer 19

Question 20

What is mucosal immunity?

Answer 20

Question 21

What is neonatal immunity?

Answer 21

Question 22

Explain Ig half time expansion in neonates

Answer 22

Question 23

What viruses undergo immunogenic invasion?

Answer 23

Question 24

What microbes inhibit complement activation?

Answer 24

Question 25

What microbes block hyalauronic acid?

Answer 25

Question 26

Describe the third line of defense of the immune system

Answer 26

Question 27

What is natural immunity?

Answer 27

Natural immunity: acquired as part of normal life experiences
• Active or passive

Question 28

What is artificial immunity?

Answer 28

Artificial immunity: acquired through a medical procedure
such as a vaccine
• Active or passive

Question 29

What is active immunity?

Answer 29

▪ Active immunity: results when a person is challenged with antigen that stimulates production of antibody.
• It creates memory, takes time and is lasting

Question 30

What is passive immunity?

Answer 30

▪ Passive immunity: pre-formed antibody are donated to an
individual.
• It does not create memory, acts immediately, and is short term.

Question 31

Breakdown examples of adaptive immunity

Answer 31

Question 32

Contrast active and passive immunity

Answer 32

Question 33

What factors go into vaccine development?

Answer 33

Question 34

Whaat are the most difficult vaccine challenges?

Answer 34

Question 35

What are whole vaccines?

Answer 35

1) Whole vaccines
• Killed whole bacterial cells or inactivated virus
• Live, attenuated bacterial cells or virus

Question 36

What are acellular or subunit vaccines?

Answer 36

2) Acellular or subunit vaccine
• Antigens derived from bacterial cells or virus particles
• Typically, surface molecules or neutralized toxins (toxoid)

Question 37

What are recombinant vaccines?

Answer 37

3) Recombinant vaccine
• Genetically engineered
• Selected genes for microbial antigens are cloned into a vector

Question 38

What are killed whole bacterial vaccine and inactivated whole viral vaccines?

Answer 38

Question 39

What is attenuation ?

Answer 39

Question 40

What’s the significance of live attenuated vaccines?

Answer 40

Question 41

What’s the significance of acellular and subunit vaccines?

Answer 41

Question 42

What are the types of recombinant vaccines?

Answer 42

Question 43

What’s the significant physical aspects of COVID 19?

Answer 43

Question 44

How do3s an mRNA vaccine function?

Answer 44

Question 45

Compare the types of vaccines?

Answer 45

Question 46

Describe the immunization in the fetus and neonate

Answer 46

Question 47

Describe the timing of production of immunoglobins

Answer 47

Question 48

What are the types of childhood vaccinations?

Answer 48