HY Review #2 Flashcards
Epigastric pain radiating to the back
Dx/ATx/ChTx?
acute pancreatitis
Acute
1st Normal Saline
NSAIDs → Hydromorphone
NGT → Start early Oral feeding as soon as tolerated
Chronic
Insulin (likely has DM)
Pancreo-lipase (pancreatic enzyme replacement therapy)
Imaging finding in Pancreatitis
Calcifications in Pancreas
Bad prognostic factors in pancreatitis?
(3)
Very High Wbc (>16k)
Low Hb
Hypocalcemia
Indicate → Hemorrhagic Pancreatitis
HTN that has remained poorly responsive to amlodipine, HCTZ, and prazosin therapy.
Labs are notable for: K 2.9L, Bicarb 29H, and Na 139.
Dx/Tx?
Conn Syndrome
(Primary hyperaldosteronism s/t adrenal adenoma)
Tx based if unilateral or bilateral
Unilateral ↑ Aldosterone on adrenal vein sampling: → unilateral adrenalectomy
Bilateral → MR antagonist (Spironolactone/Eplerenone)
In Primary hyperaldosteronism (s/t adrenal adenoma)
Renin levels: ___
Angiotensin 1 and 2 levels: ___
PAC/PRA: ___
Response to saline infusion: ___
↓ Renin
↓ Ang I & II
↑ >30 (High Aldo/Low Renin = High ratio)
Saline will not suppress aldosterone levels (Diagnostic)
BP is 250/140 with AMS.
NBSIM?
HTN emergency
Clevidipine, Nicardipine, Nitroprusside, Labetalol, or
Phentolamine (alpha 1 blocker)
(HTN urgency = no end organ dmg. same tx)
SBO + air in the wall of the biliary tree (Pneumobilia)
Dx/Tx?
Gallstone illeus
Entero-lithotomy (incise terminal illeum)
Hypodense hepatic mass with peripheral enhancement (Halo) on arterial phase and centripetal filling on delayed phases.
Dx/NBSIM?
Hepatic hemangioma
Liver finding that YOU DO NOT TOUCH
Stellate scar on liver seen abdominal CT
Dx/NBSIM?
Focal nodular hyperplasia
DO NOT TOUCH MASS
Heterogeneous enhancement in Liver on CT.
Dx/NBSIM?
Hepatic adenoma
Avoid Estrogen containing contraceptives
DO NOT TOUCH
Animal/Human Bite wound
NBSIM?
Debride (clean)
Amoxicillin
→ DO NOT stitch closed bc anaerobes present
→allow to heal via secondary intention
MCCOD in refeeding syndrome?
HYPOPHOSPHATEMIA
(causes cardiac problems)
RUQ pain, direct hyperbilirubinemia & scleral icterus (jaundiced).
No fever
Dx/NBSIM/Tx (2)?
Choledocolithiasis
RUQ abd U/S
If CBD dilated → ERCP → Cholecystectomy
(stone obstructs bile duct trapping bilirubin → jaundice)
RUQ pain, direct hyperbilirubinemia (jaundiced) & FEVER
± AMS & Hypotension
Dx/Tx (2)?
Acute Cholangitis
ERCP (diagnostic and therapeutic ) + Ceftriaxone
(Ascending biliary tract infection)
RUQ pain and FEVER
Winces upon deep palpation of the RUQ.
Labs: ↑ wbcs, mild↑AST/ALT
normal bilirubin, ALP/GGT
Dx/Tx?
Acute Cholecystitis
RUQ U/S
Cholecystectomy
pt with 30 pack year smoking history with rapidly developing digital clubbing and diffuse joint pain
Dx/NBSIM?
Hypertrophic Pulmonary Osteoarthropathy
Chest CT (r/o likely lung cancer; paraneoplastic)
Small Cell Lung Cancer Paraneoplastic Complications:
SIADH causes ____.
Lambert Eaton Myasthenia Syndrome ____.
Bonus: can also cause ____
SIADH → Hyponatremic seizures
LEMS → Proximal muscle weakness
(Difficulty combing hair/raising from chair)
Hypercortisolism (Cushing’s Syndrome)
auto anti-bodies against PRE synaptic voltage gated Ca channels
Facial swelling, headaches, and bilateral JVD
Dx/Tx?
SVC syndrome
EMERGENT RADIOTHERAPY
(SVC external compression from tumor)
2 mm L sided pupils with a droopy eyelid and L sided hand (or shoulder) pain.
Dx s/t ___
Horner Syndrome
s/t Pancoast Tumor ( aka Superior Sulcus Tumor)
Tumor compresses cervical sympathetic chain
TIP: Always check the apical lung tumor in smokers CXR
NBSIM in lung nodule seen on CXR
Chest CT
(don’t bother with the old CXR)
How to biopsy Central Lung lesions:
Endobronchial ultrasound + biopsy
or
Mediastinoscopy + biopsy
How to biopsy Peripheral Lung lesions?
percutaneous CT guided biopsy
(if lesion on the outer edge)
Pt with lung nodule on CXR and pleural effusion
NBSIM?
Thoracentesis (w/ cytology)
Where to insert needle when doing a
1. Thoracentesis
2. Nerve Block
- ABOVE the rib to avoid intercostal bundle under the rib
- BELOW the rib to reach the intercostal bundle
Pt has thickened lung pleura and/or hemorrhagic pleural effusions
Dx?
Mesothelioma
(cancer of pleura)
(+) Psammoma bodies
(concentric, lamellated microscopic calcifications)
Squamous Cell Lung Cancer treatement?
Chemotherapy only
(all other lung cancers can have any treatment)
Major determinant of successful TB tx?
Medication Adherence
Pt presents with (+) TB skin test, but negative chest X-ray.
NBSIM?
Latent TB
Isoniazid + Vit B6 (9m)
Asymptomatic patient with INR of 9 on Warfarin
NBSIM?
prothrombin complex concentrate (PCC)
± oral vitamin K
Pt presents with abdominal pain
Takes chronic Warfarin
Labs: ↓ Hgb 9 & INR 9
Dx?
Intra-abdominal hematoma
65M with 6 mo history of progressively worsening dyspnea, dry cough, and bibasilar fine crackles heard on lung auscultation.
Dx/NBSIM?
Idopathic pulmonary fibrosis
High Resolution CT Chest
(on NBME: Fine crackles = Fibrotic lung disease)
60M with 1 week h/o of blurry vision and severe headache. PE shows splenomegaly and markedly swollen/tender hand & feet joints with overlying erythema.
Labs: ↓↓↓ Hgb (6.5), ↑↑↑ Plts (900k), ↓↓ WBC (1.2K)
Dx/Tx(2)?
Essential Thrombocytosis
Platelet-pharesis + Aspirin
(JAK 2 mutation; hypercoagulable)
– Only one cell line is absurdly high, while all others are low → think myeloproliferative d/o
60M 3 week of worsening pruritus (not improved with diphenhydramine) & worse when showering.
PE shows flushed/roddy pt & spelnomegaly
Labs: ↑↑↑ Hct (70%)
Dx/Tx?
Polycythemia Vera (PV)
Phlebotomy
In PV: ↓EPO b/c negative feedback from ↑Hct
(vs paraneoplastic 2º polycythemia where EPO is incr.)
Myeloproliferative d/o + JAK 2 mutation
• PV
• Essential Thrombocythemia
• Myelofribrosis (dry tap/teardrop rbcs)
List 2 common causes of Budd Chiari Syndrome on NBMEs
Polycythemia Vera
PNH
(Paroxysmal Nocturnal Hemoglobinuria)
Intermittent & fatigable proximal muscle weakness
(initial evaluation may be normal bc comes & goes)
worsens with repetitive/prolonged motions
improves with rest
± ocular/oral sxs
Dx/Tx
Myastenia Gravis
Pyridostigmine (AChE inhibitors)
Auto-ABs to postsynaptic acetylcholine receptors of NMJ
Myasthenic crisis → exacerbation leads to respiratory failure
tx: serial spirometry + IVIg or plasma exchange
Elderly pt presents with Fever + acute LLQ abd pain + change in bowel movements.
Leukocytosis
Dx/NBSIM/Tx(2)?
Diverticulitis
CT A/P
Peritoneal sxs → Colectomy sigmoid
Conservative (bowel rest & analgesia)
or FQ+Metronidazole
Elderly pt presents with acute LLQ abd pain & bloody diarrhea
low-grade fever + mild Leukocytosis
Recent hx of MI or A-fib
Dx/tx (3)?
Ischemic Colitis
(supportive care + Abxs + anticoagulation)
Opioid adverse side effects include (3):
Miosis (Constricted pupils)
Sedation (AMS)
Hypotension
Constipation
Bradycardia
Depressed respiratory drive
Mnemonic: MS. CBD
Normal rate of Respiration: 12 –16 bpm