Drug Rxns Flashcards
Agranulocytosis caused by what meds (3)
PTU/Methimazole
carbamazepine
Clozapine
Indicated for organophosphate toxicity, which presents with altered mental status typically after exposure to agricultural pesticides.
Atropine
signs of cholinergic excess (eg, salivation, urination, diarrhea, bradycardia) are present
Drug-Induced Lupus by what meds?
procainamide
Hydralazine,
Isoniazid,
Etanercept,
Phenytoin
sulfonamies (TMP-SMX)
Drugs that cause pulmonary fibrosis (3)
Methotrexate
Amiodarone
Bleomycin/Busulfan
respiratory difficulty occurs a few hours after medication for MI
Aspirin-Induced Asthma
Beta blocker use in Asthmatic
most common cause of drug-induced hepatitis/liver failure
Acetaminophen
Hepatotoxic meds (4)
TB drugs (Rifampin, Isoniazid)
Acetaminophen
Statins
Amiodarone
Amiodarone: Check (2)
antiarrhythmic
LFTs
PFTs
___ torches the stomach (hemorrhagic gastritis)
X-ray: can see the pills
Iron
Tetracycline can cause what skin problem
Photosensitivity
2 Drugs that can cause cinchonism
tinnitus
hearing loss
visual problems
± hemolytic anemia
Salicylic Acid
Quinidine
(arrhythmias & malaria)
Patients with ____ deficiency at HIGHER risk of Methemoglobinemia
G6PD deficiency
2 Drugs that cause IRREVERSIBLE dilated cardiomyopathy
Prevent with Dexrazoxane (iron chelator)
Doxorubicin/Daunorubicin
(Traztuzumab = reversible cardiomyopathy)
Peripheral neuropathy causing drugs (3)
TB patient (Isoniazid)
Anti-cancer drugs (Vincristine/Vinblastine)
Hemorrhagic cystitis can be caused by ___ virus and the drug ___
ADENOVIRUS
Cyclophosphamide
* Churg-Straus (eosinophilic GPA)
*Wegener’s (Granulomatosis with Polyangiitis)