Drug Rxns Flashcards

1
Q

Agranulocytosis caused by what meds (3)

A

PTU/Methimazole
carbamazepine
Clozapine

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2
Q

Indicated for organophosphate toxicity, which presents with altered mental status typically after exposure to agricultural pesticides.

A

Atropine

signs of cholinergic excess (eg, salivation, urination, diarrhea, bradycardia) are present

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3
Q

Drug-Induced Lupus by what meds?

A

procainamide
Hydralazine,
Isoniazid,
Etanercept,
Phenytoin
sulfonamies (TMP-SMX)

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4
Q

Drugs that cause pulmonary fibrosis (3)

A

Methotrexate
Amiodarone
Bleomycin/Busulfan

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5
Q

respiratory difficulty occurs a few hours after medication for MI

A

Aspirin-Induced Asthma
Beta blocker use in Asthmatic

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6
Q

most common cause of drug-induced hepatitis/liver failure

A

Acetaminophen

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7
Q

Hepatotoxic meds (4)

A

TB drugs (Rifampin, Isoniazid)
Acetaminophen
Statins
Amiodarone

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8
Q

Amiodarone: Check (2)

antiarrhythmic

A

LFTs
PFTs

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9
Q

___ torches the stomach (hemorrhagic gastritis)
X-ray: can see the pills

A

Iron

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10
Q

Tetracycline can cause what skin problem

A

Photosensitivity

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11
Q

2 Drugs that can cause cinchonism
tinnitus
hearing loss
visual problems
± hemolytic anemia

A

Salicylic Acid
Quinidine
(arrhythmias & malaria)

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12
Q

Patients with ____ deficiency at HIGHER risk of Methemoglobinemia

A

G6PD deficiency

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13
Q

2 Drugs that cause IRREVERSIBLE dilated cardiomyopathy
Prevent with Dexrazoxane (iron chelator)

A

Doxorubicin/Daunorubicin

(Traztuzumab = reversible cardiomyopathy)

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14
Q

Peripheral neuropathy causing drugs (3)

A

TB patient (Isoniazid)
Anti-cancer drugs (Vincristine/Vinblastine)

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15
Q

Hemorrhagic cystitis can be caused by ___ virus and the drug ___

A

ADENOVIRUS
Cyclophosphamide
* Churg-Straus (eosinophilic GPA)
*Wegener’s (Granulomatosis with Polyangiitis)

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16
Q

Patient with excess vomiting who is being treated for cancer.
Dx → Platinum-compound chemotherapy (2)

A

cisplatin
oxaliplatin

tx: Ondansetron