Hushingtons Disease - Pharmacology Flashcards
1
Q
What is Hushingtons Disease?
A
OVERACTIVE DOPAMINE ACTIVITY !!!!!!!!!!
Progressive neurodegeneration
Genetic disorder: trinucleotide repeat in protein huntingtin
Motor: loss of striatal spiny neurones and dysfunctional basal ganglia activity
Hyperkinesia: writhing, jerky movements. Cognitive and mood disorders.
2
Q
What is the treatment for Huntingtons treatment ?
A