Hostology Of The Liver Pancreas And Billary Tract Flashcards

1
Q

What is the liver divided into

A

Classic lobules

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2
Q

What is a classic lobule

A

It is an area drained by one central hepatic venule

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3
Q

What shape are the lobules

A

Hexagonal

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4
Q

What is the acinus

A

Architectural concept based around the blood supply rather than the drainage

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5
Q

What does the hepatic triad include

A

Bile duct
Portal vein
Hepatic artery

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6
Q

What are Hepatocytes and what are they composed of

A

Functional cells of the liver

Polyhedral epithelial cells
Abundant mitochondria
Large central spherical nucleus
Prominent nucleoli
Could be binucleate

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7
Q

What are the 3 important surfaces of hepatocytes

A

Sinusoidal
Canalicular
Intercellular

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8
Q

What are sinusoids and what do they contain

A

Highly specialised blood vessels

They have thin discontinuous fenestrated endothelium
No basement membrane
Contains scattered kupffer cells

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9
Q

What epithelial change is seen in the intrahepatic biliary tree

A

Simple cuboidal to columnar epithelium

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10
Q

What are the functions of the gall bladder

A

Concentrates and stores bile
Expels bile via common bile duct into duodenum

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11
Q

The gall bladder is made up of a specialised mucosa what is this made up of

A

Simple columnar epithelium
Microvilli
Folded membrane
Connective tissue
Lamina propria

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12
Q

What is the function of the pancreas

A

To synthesise and secrete enzymes and bicarbonate rich fluid into the duodenum

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13
Q

What makes up the pancreas

A

Poorly defined fibrous capsule with septa dividing the gland into lobules

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14
Q

How are the epithelial cells arranged in the pancreas

A

They are arranged in acini

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15
Q

What are characteristics of acinar cells and where are they found

A

They are found in the pancreas

They are epithelial cells which are pyramidal in shape and rich in rough endoplasmic reticulum

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16
Q

What are the different ducks found in the pancreas

A

Centroacinar cells
Intercalated ducts
Interlobular ducts
Main pancreatic ducts

17
Q

How are hepatocytes arranged

A

Arranged in plates around central veins

18
Q

What are the arrows labelling

A

The top arrow is labelling the portal triad made up of a hepatic vein, hepatic artery and bile duct

The second arrow is labelling the hepatocytes arranged in cords with intervening sinusoids

The third arrow is labelling the central veins

19
Q

Where is this tissue taken from

A

The liver showing hepatocytes

20
Q

What is the arrow pointing at

A

Sinusoids

21
Q

What is the arrow pointing to

A

Bile ductules

22
Q

What are the arrows labelling and where is the tissue taken from

A

The first arrow is labelling the specialised mucosa
The second arrow is labelling the smooth muscle layer

Tissue is from the gall bladder