Hostology Of The Liver Pancreas And Billary Tract Flashcards
What is the liver divided into
Classic lobules
What is a classic lobule
It is an area drained by one central hepatic venule
What shape are the lobules
Hexagonal
What is the acinus
Architectural concept based around the blood supply rather than the drainage
What does the hepatic triad include
Bile duct
Portal vein
Hepatic artery
What are Hepatocytes and what are they composed of
Functional cells of the liver
Polyhedral epithelial cells
Abundant mitochondria
Large central spherical nucleus
Prominent nucleoli
Could be binucleate
What are the 3 important surfaces of hepatocytes
Sinusoidal
Canalicular
Intercellular
What are sinusoids and what do they contain
Highly specialised blood vessels
They have thin discontinuous fenestrated endothelium
No basement membrane
Contains scattered kupffer cells
What epithelial change is seen in the intrahepatic biliary tree
Simple cuboidal to columnar epithelium
What are the functions of the gall bladder
Concentrates and stores bile
Expels bile via common bile duct into duodenum
The gall bladder is made up of a specialised mucosa what is this made up of
Simple columnar epithelium
Microvilli
Folded membrane
Connective tissue
Lamina propria
What is the function of the pancreas
To synthesise and secrete enzymes and bicarbonate rich fluid into the duodenum
What makes up the pancreas
Poorly defined fibrous capsule with septa dividing the gland into lobules
How are the epithelial cells arranged in the pancreas
They are arranged in acini
What are characteristics of acinar cells and where are they found
They are found in the pancreas
They are epithelial cells which are pyramidal in shape and rich in rough endoplasmic reticulum