Hostology Of The Liver Pancreas And Billary Tract Flashcards
What is the liver divided into
Classic lobules
What is a classic lobule
It is an area drained by one central hepatic venule
What shape are the lobules
Hexagonal
What is the acinus
Architectural concept based around the blood supply rather than the drainage
What does the hepatic triad include
Bile duct
Portal vein
Hepatic artery
What are Hepatocytes and what are they composed of
Functional cells of the liver
Polyhedral epithelial cells
Abundant mitochondria
Large central spherical nucleus
Prominent nucleoli
Could be binucleate
What are the 3 important surfaces of hepatocytes
Sinusoidal
Canalicular
Intercellular
What are sinusoids and what do they contain
Highly specialised blood vessels
They have thin discontinuous fenestrated endothelium
No basement membrane
Contains scattered kupffer cells
What epithelial change is seen in the intrahepatic biliary tree
Simple cuboidal to columnar epithelium
What are the functions of the gall bladder
Concentrates and stores bile
Expels bile via common bile duct into duodenum
The gall bladder is made up of a specialised mucosa what is this made up of
Simple columnar epithelium
Microvilli
Folded membrane
Connective tissue
Lamina propria
What is the function of the pancreas
To synthesise and secrete enzymes and bicarbonate rich fluid into the duodenum
What makes up the pancreas
Poorly defined fibrous capsule with septa dividing the gland into lobules
How are the epithelial cells arranged in the pancreas
They are arranged in acini
What are characteristics of acinar cells and where are they found
They are found in the pancreas
They are epithelial cells which are pyramidal in shape and rich in rough endoplasmic reticulum
What are the different ducks found in the pancreas
Centroacinar cells
Intercalated ducts
Interlobular ducts
Main pancreatic ducts
How are hepatocytes arranged
Arranged in plates around central veins
What are the arrows labelling
The top arrow is labelling the portal triad made up of a hepatic vein, hepatic artery and bile duct
The second arrow is labelling the hepatocytes arranged in cords with intervening sinusoids
The third arrow is labelling the central veins
Where is this tissue taken from
The liver showing hepatocytes
What is the arrow pointing at
Sinusoids
What is the arrow pointing to
Bile ductules
What are the arrows labelling and where is the tissue taken from
The first arrow is labelling the specialised mucosa
The second arrow is labelling the smooth muscle layer
Tissue is from the gall bladder
