Histology Of The Urinary Tract Flashcards
What makes up the nephron
Glomerulus
Proximal convoluted tubule
Thick limb of loop of henle
Thin limb of the loop of henle
Distal convoluted tubule
Collecting duct
What are the different parts of the kidney
Cortex
Medulla
Pelvis
What are characteristics of the glomerulus
Tufts of convoluted fenestrated capillaries
Glomerular basement membrane
Lined by podocytes
Supported by mesangial cells
Encased in bowman’s capsule
What are the 2 components of the juxtaglomerular apparatus
Afferent arteriole
Distal convoluted tubule
What is the role of the juxtaglomerular apparatus
Secretes renin in response to low blood pressure
What does the distal convoluted tubule contribute to in the juxtaglomerular apparatus
The macula densa
What are characteristics of the proximal convoluted tubule
Cuboidal epithelium
Round central/basal nuclei
Brush border of microvilli at apical end
Many mitochondria
What is the role of the proximal convoluted tubule
Reabsorption of NaCl, proteins, polypeptides, amino acids and glucose
What are characteristics of the loop of henle
Made up of descending and ascending limbs
Thick and thin segments
Thin = simple squamous
Thick = low cuboidal
Supplied by rich vasa recta
What are characteristics of the distal convoluted tubule
Low cuboidal epithelium
Scanty microvilli
Numerous mitochondria
What is the role of the distal convoluted tubule
Regulates acid base by secreting H+ and absorbing HCO3- via cellular carbonic anhydrase
Regulates Na levels by exchanging Na for K
What are the characteristics of the collecting ducts
Cuboidal epithelium
Principal cells
Intercalated cells
What is the role of the principal cells of the collecting duct
They respond to aldosterone and ADH
What is the role of intercalated cells of the collecting duct
Exchanges H+ for HCO3-
Where does the kidneys blood supply originate from
Abdominal aorta
At what level does the the real artery level the abdominal aorta
The renal artery levels at the level of L1
Where does the loop of henle descend into
Descends into the medulla
What lines the renal pelvis
Urothelium