hormonal communication Flashcards

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1
Q

endocrine gland

A

secretes its product directly into blood ( lymph)

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2
Q

target cells

A

possess a specific receptor on cell surface membrane, complementary hormone

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3
Q

exocrine gland

A

secretes its products in a duct

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4
Q

endocrine system

A

group of glands that release hormones into blood

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5
Q

eg of glands

A

pituitary gland - LH & FSH
pancreas - insulin

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6
Q

protein hormones

A

INSOLUBLE over bilayer
-bind to cell surface and release as secondary messenger inside cell
(Enzyme catalyses second messenger)

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7
Q

steriod hormones

A

can pass through the membrane & enter cell and nucleus
-has an effect on DNA in the nucleus

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8
Q

adrenaline

A

hormone released from adrenal glands
-stimulates breakdown of proteins & fats into glucose
-increases blood volume and pressure
-uses cholesterol to produce steroid hormones when stressed

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9
Q

adrenal glands

A

Found on top of kidneys
-each gland has outer layer (cortex)
-good blood supply - to transport adrenaline straight into blood

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10
Q

adrenal cortex

A

zona glomerolusa (outer layer)
secretes mineral orcoticoids eg aldosterone (that regulates blood pressure)

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11
Q

adrenal medulla

A

secretes adrenaline and nor-adrenaline in response to stress
short term response - increased HR and BR
increased rate of glycogen breakdown into glucose
nor-adrenaline is just always in circulation and work together to increase HR

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12
Q

3 regions of adrenal gland

A

zona glomerulosa
zona fasciculata - middle layer secretes glucorticoids (cortisol increases sugar levels)
zona reticularis (inner layer) secretes precursor molecules (androgens -sex hormones)

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13
Q

pancreas

A

gland found below stomach
made of 2 cell types ( alpha & beta)

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14
Q

hypoglycemia

A

low blood sugar

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15
Q

hyperglycemia

A

high blood sugar

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16
Q

when low blood sugar

A

alpha cells in islets of langerhans detect low sugar level
alpha cells then secrete glucagon
target cells in liver have a receptor for glucagon where glycogenolysis occurs to produce more glucose into the blood

17
Q

when high blood sugar

A

beta cells in the islets of langerhans detect high sugar level
beta cells then secrete insulin
insulin binds to receptors on liver
(tyrosine kinase activated)
glycogenesis occurs to reduce glucose level

18
Q

type 1 diabetes symptoms

A

hyperglycemia
-excretion of glucose in urine
-excessive thirst and hunger
-weight loss

19
Q

type 1 diabetes

A

auto-immune disease
body doesnt produce insulin
treatments = pancreas transplant, healthy balanced diet, excercise

20
Q

type 2 diabetes

A

body doesnt react to insulin
insulin is still produced
linked with obesity
normally acquired later in life

21
Q

type 2 diabetes treatments

A

medication to either increase insulin release or make the beta cells more sensitive to insulin