Homeostatic Imbalances of Bone - notes Flashcards
Caused by insufficient Vitamin D or
calcium.
OSTEOMALACIA & RICKETS
Caused by insufficient Vitamin C.
SCURVY
Caused by decreased ESTROGEN production after menopause.
OSTEOPOROSIS
The osteoid material of bone is normal, but no calcium is added. This makes the bones abnormally soft.
OSTEOMALACIA & RICKETS
Estrogen has a protective effect on the skeleton throughout life:
It limits the amount of bone breakdown that is caused by parathyroid
hormone.
OSTEOPOROSIS
The collagen in the bone & in all body tissues is abnormal. This means the bones are full of holes, and very brittle.
SCURVY
Adult version of insufficient Vitamin D.
OSTEOMALACIA
Has abnormal collagen. (has holes in it)
SCURVY
Symptoms: Anemia, hemorrhaging, poor health, gingivitis, holes in bones.
SCURVY
At menopause, estrogen levels fall off drastically. The low levels of estrogen
can no longer keep PTH in check—so osteoclast activity shoots up, causing
bone breakdown to get out of control.
OSTEOPOROSIS
Bones soften, muscle weakness, bone pain; fractures
OSTEOMALACIA
No calcium added to bones so bones are soft and deformed especially in the pelvic bone and legs.
RICKETS
Overproduction of Parathyroid hormone, Inadequate
absorption of Calcium, Inadequate Intake of Calcium, Vitamins D or C.
OSTEOPOROSIS