Homeostasis Flashcards
what plays/ does not play a role in homeostatic balance?
-balance maintained by collective action of urinary, respiratory, digestive, endocrine, nervous, cardiovascular, and lymphatic systems
dehydration role in homeostasis and when ADH is secreted
- dehydration is when water loss is greater than gain. The decrease in volume increases osmolarity of fluids and stimulates the thirst center in the hypothalamus
- in turn raises ADH (anti diuretic hormone) secretion so water will be retained (hypothalamus is signaled to release ADH to retain water)
where is most water in our body found?
- intercellular fluid (inside cells): 65%
- 2/3 of body fluid
where does most of the water in our body come from and how is most of it lost?
- comes mostly from ingestion of liquids and food (2300mL/day), and metabolic synthesis of water during cellular respiration and dehydration synthesis (200mL/day)
- mostly lost from kidneys (urination) (1500mL/day), evaporation from skin (sweat) (600mL/day), exhalation from lungs (300mL/day), and feces (100mL/day)
what percentage of our body composition does water account for?
55% females; 60% males
what governs fluid intake?
thirst center in hypothalamus increases thirst and water intake
what does the ADH hormone produced in the hypothalamus promote?
- regulates water loss
- increases water permeability in urine
- produces concentrated urine
what are some long term inhibitions of thirst?
- decreased flow of saliva -> dry mouth and pharynx
- increased blood osmolarity -> stimulates osmoreceptors in hypothalamus
- decreased blood volume -> decreased blood pressure -> increased renin release in kidneys -> increased angiotensin II formation
bicarbonate buffer system chemical equation
CO2 + H2O H2CO3 HCO3- + H+
- can do right winded reaction to lower pH by releasing H+
- can do left winded reaction to raise pH by binding H+
what are some major chemical buffer systems of the body?
- protein buffer system
- bicarbonate buffer system
- phosphate buffer system
what is the normal pH level for the body and tissue fluid?
7.35- 7.45
respiratory acidosis/ alkalosis and was causes these
- results from changes in partial pressure of CO2 in systemic arterial blood
- acidosis= abnormally high PCO2 in systemic arterial blood; inadequate exhalation of CO2; caused by any condition that decreases mvmt of CO2 out of lungs (emphysema, pulmonary edema, etc); treatment is ventilation
- alkalosis= abnormally low PCO2 in systemic arterial blood; caused by hyperventilation due to oxygen deficiency from high altitude, pulmonary disease, stroke, severe anxiety; treatment is breathing into paper bag
four general functions of electrolytes
- control osmosis of water between body fluid compartments
- help maintain acid- base balance
- carry electrical current (brain and heart function)
- serve as cofactors (need electrolytes to get to threshold for signals to move muscles)
metabolic acidosis/ alkalosis and was causes these
- kidneys
- Results from changes in bicarbonate (HCO3-) concentration
- acidosis= abnormally low HCO3 in systemic arterial blood; caused by severe diarrhea, renal disfunction, accumulation of acid other than carbonic acid (ketosis), failure of kidneys to excrete H+ from metabolism of dietary proteins; hyperventilation can help, IV of sodium bicarbonate can correct
- alkalosis= Abnormally high HCO3- in systemic arterial blood; caused by non respiratory loss of acids (vomiting stomach acid), excessive intake of alkaline drugs (antacids), use of certain diuretics, severe dehydration; hyperventilation can help, fluid solutions to correct Cl-, K+ and other electrolyte deficiencies
respiratory acidosis/ alkalosis and was causes these
- lungs
- results from changes in partial pressure of CO2 in systemic arterial blood
- acidosis= abnormally high PCO2 in systemic arterial blood; inadequate exhalation of CO2; caused by any condition that decreases mvmt of CO2 out of lungs (emphysema, pulmonary edema, etc); treatment is ventilation
- alkalosis= abnormally low PCO2 in systemic arterial blood; caused by hyperventilation due to oxygen deficiency from high altitude, pulmonary disease, stroke, severe anxiety; treatment is breathing into paper bag